Thienopyrimidine derivatives are well-known in various pharmaceutical and biomedical domains. In this work, a series of efficacious and novel strategies for the synthesis of thienopyrimidines starting from 2-amino-3-carboethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene has been developed. The regioselectivity of these synthetic strategies was investigated using density functional theory computation and spectroscopic analysis. In addition, the chemical structures of the new thienopyrimidines and their reaction mechanisms, as well as the biological activity of selected compounds were studied.

Nanomaterials with controllable particle size and shape have fascinating properties. Herein, CuO nanoparticles (NPs) with controlled particle size and morphology are obtained via a simple co-precipitation approach. Variation of the reaction medium composition steers the variation of both particle size and morphology of the CuO NPs. The reaction was performed in ethanol–water solutions with different volume to volume ratios (v/v%) i.e. 0, 25, 50, and 100%. XRD of the obtained samples revealed a drop in their particle size from ∼13 to ∼7 nm when the aqueous medium is entirely replaced by the ethanolic medium. TEM and HR-TEM investigations have pointed to the formation of CuO NPs with rod-like shapes in water (diameter = 15 nm and length = 200 nm). Whereas, spherical NPs with a diameter of 7.2 nm are obtained in ethanol. Structural analysis of CuO samples obtained in different media was done …

Fresh water is becoming increasingly scarce in Taiz city, Yemen, partly due to a growing population and in part due to pollution of near surface aquifers by municipal and industrial wastes. Electrical depth sounding has been found to be powerful tool to delineate subsurface contaminated zones. The measured apparent resistivity and 1D inversion models have been used to construct apparent maps and 2D geoelectrical cross-sections displaying the variation of resistivity of the subsurface layers.

In the present study, a vertical electrical sounding (VES) was conducted using the shlumberger array at 38 sites distributed over six profiles along the most important wadis in the Uplands Wadi Rasyan, Taiz, Yemen. The objectives of this study were:(1) to locate the distribution of contamination zones, and (2) to investigate the

Surface geophysical investigations, in addition to hydrochemical measurements were made on some locations at the western part of the River
Nile, Assiut. All the geoelectrical sounding measurements were made using the D.C. resistivity method. The geophysical results were
integrated with all available geological and hydrogeological information in order to recognize the probability of presence of water-bearing
formations, either fresh (low resistivity) or polluted (extremely low resistivity). Two conductive wet zones (shallow and/or deep) were
detected. Also, two extremely high resistive zones can be recognized; the first represents the surface dry zone (consisting of dry sands and
gravels), whereas the second is deeper in the entire surveyed area and may represent the bed rock (e.g. limestone). Only one extremely
conductive zone (< 20 Ohm-m) especially near and at the cultivated land in El-Madabigh and Beni-Adi is present, which may correspond to
clayey sediments or a polluted zone. The hydrochemical data show that the salinity decreases along the regional direction of the groundwater
flow and also along the sewage water movement in the irrigation canals.

The study of groundwater potential in Wadi El-Assiuoti is of a prime importance for both current and future
development. In this paper the groundwater occurrences are investigated using integrated; 1) geophysical well
logging (Self potential, Resistivity and Gamma Ray), 2) subsurface lithologic data and 3) hydraulic data
(transmissivity, transmissibility, hydraulic conductivity and storativity) in addition to reviewing all studies on
Wadi El-Assiuoti. Different petrophysical parameters (formation water resistivity, formation factor, porosity,
permeability, salinity and shale volume) are computed. These parameters are very necessary to identify the
aquifers characteristics in the surveyed area. The integration between geophysical and hydrogeological data
shows the possibility of two water bearing formation (Quaternary and Plio-Pleistocene). Generally, porosity and
permeability values of these aquifers decrease toward the west. The aquifers exist under unconfined to semi
confined conditions. The wide range values of both well efficiency and hydraulic conductivity indicate heterogeneity
in the lithology and hydraulic characteristics of the aquifer materials. The computed transmissibility
values indicate that the water-bearing sediments in the area under investigation are generally of high productivity.
In some localities due to the heterogeneity of sediment, the water-bearing sediments are of moderate
productivity. Recently, due to the increase of drilling activities at the middle part of the studied area some
problems concerning the groundwater potential and high salinity in the area are happening.