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Congratulation

Professor Gihan Nabil Hassan Fetih

Dean of Faculty of Pharmacy, Assiut University

Congratulations to the Faculty  family

for the Faculty  winning the Automated Access Grant

(Instrumental Access)

To provide laboratory equipment and supplies to support and develop scientific research at the Faculty

It extends its sincere thanks and appreciation to

Prof. Dr. Mustafa Ahmed Hussein - Head of the Department of Pharmaceutical Organic Chemistry

Dr. Rana Muhammad Ibrahim - Lecturer in the Department of Pharmaceutical Organic Chemistry and the family of the Department of Pharmaceutical Organic Chemistry

This is due to their efforts to obtain the grant

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خبر عام

Important announcement for students of the Bachelor of Pharmacy program

Students enrolled in the different teams must quickly complete their registration Courses, The last date for adding and deleting courses is Sunday, February 25, 2024, and student names will not be added to the lists of course names after this date.

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إعلانات الطلاب

A workshop for Faculty students entitled (CV writing skill)

ورشة عمل لطلاب الكلية تحت عنوان : - مهارة كتابة السيرة الذاتية

ورشة عمل لطلاب الكلية تحت عنوان : - مهارة كتابة السيرة الذاتية

Under the patronage of Prof. Dr. Ahmed El-Minshawy - President of the University, Prof. Dr. Ahmed Mohamed Abdel Mawla - Vice President of the University for Education and Student Affairs, and Prof. Dr. Mahmoud Abdel Aleem - Vice President of the University for Community Service and Environmental Development Affairs, and under the supervision of Prof. Dr. Gihan Nabil Fateh - Acting Dean of the Faculty , Prof. Dr. Hassan Refaat Hassan - Vice Dean for Education and Student Affairs, and Prof. Dr. Mohamed Mahmoud Abdel Latif - Vice Dean for Community Service and Environmental Development Affairs, organized by the Faculty  of Pharmacy in cooperation with the University Center for Professional Development at Assiut University (UCCD) held a workshop for Faculty  students under the title (the skill of writing a CV). The workshop was presented by Dr. Raghda Adel Taghian - the professional development officer at the center. The organization of the workshop comes in light of preparing the students to participate in the large employment forum organized by the University Center for Professional Development.

This took place on Thursday, February 22, 2024, in the celebration hall, Building B, at the Faculty .

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خبر عام

Artistic Committee activity (Artistic workshop for painting on fabric and T-shirts)

  ورشة عمل لطلاب الكلية تحت عنوان ( مهارة كتابة السيرة الذاتية )  ورشة عمل لطلاب الكلية تحت عنوان ( مهارة كتابة السيرة الذاتية )

Under the patronage of Prof. Dr. Ahmed El-Menshawy - President of the University, Prof. Dr. Ahmed Mohamed Abdel Mawla - Vice President of the University for Education and Student Affairs, and Prof. Dr. Gihan Nabil Fateh - Acting Dean of the Faculty , the Artistic Committee of the Youth Welfare Department at the Faculty  organized a workshop. The Faculty  students worked on (drawing on fabric and T-shirts) under the supervision of Professor Dr. Hassan Refaat Hassan - the Faculty ’s dean for education and student affairs, and in the presence of Prof. Dr. Mohamed Mahmoud Abdel Latif - the Faculty ’s dean for community service and environmental development affairs and under the supervision of Prof. Dr. Hisham Mohamed. Tawfiq - Head of the Department of Industrial Pharmacy and Coordinator of Student Activities, Dr. Maryam Ashraf Amin - Lecturer in the Department of Pharmacology and Toxicology and Advisor to the Artistic Committee, Dr. Shaima Ali Abdel-Zaher - Director of the Youth Welfare Department, and the activity officials: Ms Fatima Hassan and Ms Maryam Nashaat.

This took place from 18 to 22 February 2024 in the Faculty  courtyard

 

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خبر عام

Announcement For students of the fifth year of Pharm-D for the quality control course for pharmaceuticals, the second semester of the academic year 2023/2024

God willing, the mid-term exam for students in the fifth year of Pharm-D in the quality control course for pharmaceuticals will be held on Wednesday, April 3, 2024,

at the time of the practical session (8 am-12 pm) in the department’s laboratories.

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إعلانات الطلاب

Thesis defense the Master’s degree / Marwa Mohammed Khalifa Mahmoud - Assistant Lecturer in the Department of Microbiology Registered to obtain the degree of Doctor of Philosophy in Pharmaceutical Sciences (Microbiology and Immunology) on Sunday, February

Curcumin Transferosome-Loaded Thermosensitive Intranasal in situ Gel as Prospective Antiviral Therapy for SARS-Cov-2

Research Abstract

Purpose: Immunomodulatory and broad-spectrum antiviral activities have motivated the evaluation of curcumin for Coronavirus
infection 2019 (COVID-19) management. Inadequate bioavailability is the main impediment to the therapeutic effects of oral Cur. This
study aimed to develop an optimal curcumin transferosome-loaded thermosensitive in situ gel to improve its delivery to the lungs.
Methods: Transferosomes were developed by using 33 screening layouts. The phospholipid concentration as well as the concentration
and type of surfactant were considered independent variables. The entrapment efficiency (EE%), size, surface charge, and polydispersity
index (PDI) were regarded as dependent factors. A cold technique was employed to develop thermosensitive in-situ gels.
Optimized transferosomes were loaded onto the selected gels. The produced gel was assessed based on shape attributes, ex vivo
permeability enhancement, and the safety of the nasal mucosa. The in vitro cytotoxicity, antiviral cytopathic effect, and plaque assay
(CV/CPE/Plaque activity), and in vivo performance were evaluated after intranasal administration in experimental rabbits.
Results: The optimized preparation displayed a particle size of 664.3 ± 69.3 nm, EE% of 82.8 ± 0.02%, ZP of −11.23 ± 2.5 mV, and
PDI of 0.6 ± 0.03. The in vitro curcumin release from the optimized transferosomal gel was markedly improved compared with that of
the free drug-loaded gel. An ex vivo permeation study revealed a significant improvement (2.58-fold) in drug permeability across nasal
tissues of sheep. Histopathological screening confirmed the safety of these preparations. This formulation showed high antiviral
activity against SARS-CoV-2 at reduced concentrations. High relative bioavailability (226.45%) was attained after the formula
intranasally administered to rabbits compared to the free drug in-situ gel. The curcumin transferosome gel displayed a relatively
high lung accumulation after intranasal administration.
Conclusion: This study provides a promising formulation for the antiviral treatment of COVID-19 patients, which can be evaluated
further in preclinical and clinical studies.

Research Authors
Nermin E Eleraky, Mahmoud El-Badry, Mahmoud M Omar, Wesam M El-Koussi, Noha G Mohamed, Mohamed A Abdel-Lateef, Abeer S Hassan
Research Date
Research Department
Research Journal
International Journal of Nanomedicine
Research Publisher
Dovepress
Research Rank
Q1
Research Vol
International Journal of Nanomedicine 2023:18 5831–5869
Research Website
https://www.tandfonline.com/doi/pdf/10.2147/IJN.S423251
Research Year
2023
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