Abstract Abstract: Background: Lumbar discectomy surgery is one of daily spine surgery performed. Patients complain from poor postures and/or movements that have exposed the spine to an activity to which it is not accustomed. Aim: The aim of this research was to study the effect of applying a nursing rehabilitation guide on outcomes of patients undergoing lumbar discectomy. Design: A quasi – experimental research design. Setting: orthopedic surgery department, and outpatient spine clinic at Assiut University Hospital. Subject: Purposive sample of thirty adult patients undergoing lumbar discectomy. Study tools: Three tools were utilized in this study included; structured interview questionnaire sheet include three parts; 1. Patient sociodemographic characteristics data tool, 2. Patient knowledge assessment tool, 3. Patient assessment sheet. Results: Result of current study showed a highly statistically significant improvement in patient knowledge post education than pre education at P level <0.001**, also showed improvement in patient physical state post education than pre education at P level <0.001**. Conclusion: The present study revealed that providing patients with a guide detailed with instructions for improving their knowledge was of great value and actually improves health state for those patients. Recommendations: From the present study we recommend that; providing copies of the nursing rehabilitation guide in the orthopedic department and clinic to be readily available for all patients planned to undergo lumbar discectomy, the present study be replicated on larger study populations for generalization of the results. Key words; Lumbar Discectomy, Patient outcomes, Rehabilitation