Abstract: nur ses play a crucial role in post operative care. Therefore, assessing nurses’ clinical competence is essential to achieve qualified and safe care. Aims; assess postoperative nurses' competency regarding cholecystectomy care and compare the difference between university and non - university hospitals. R esearch questions; what are the postoperative nurses' competency regarding cholecystectomy?And what are the differences betweenuniversity and non - university hospitals? Descriptive correlation research design was utilized. The study was conducted at general surgery departments of university and non - university hospitals of A ssiut city. The sample consisted of all available nurses (55nurses) who were currently assigned for giving post cholecystectomy nursing care in the above mentioned hospitals. The instruments employed for data collection were; tool one” nurses' assessment sheet", tool two “nursescompetence advanced self - assessment tool ". Results showed that; all nurses exceeded the competent level &there were significant differences between two settings regarding to their post cholecystectomy nurses’ performance competency. Conclusion: nurses have adequate knowledge, skills to adequately meet all the requirements for postoperative competency. Recommendation; the research results can be used for the educational needs assessment of nurses and for modifying the quality of care in hospitals.