Infection control in the burn patients has been a difficult problem since. Infection control in burn patients requires expertise of all practitioners interested of micro-organisms and most practice in infection control techniques to avoid spreading of infection to the burned patients. In a recent report from a burn unit, staphylococcal species, especially staph. aurous. Accounted for the majority of infections at all body sites. Thus the aim of this study was to investigate the impact of nursing intervention on the quality of nurses, performance for reducing of burn wound infection. 13 male and female nurse's working in burn unit and 90 male and female burned patients, there were divided into two equal groups for study pre- and post nursing' intervention, they were selected randomly with the following inclusion criteria: Adult patients with age more than 20 years old and all admitted to the burn unit with in 5-8 days. Nursing intervention about burn. infection control and wound dressing was developed and given to nurses. It included theoretical and practical parts. Questionnaire sheet to assess the nurse's knowledge pre- and post-intervention and check list observation sheet to assess' nurse's performances about wound dressing pre-and post- intervention. In addition to utilization of patient evaluation sheet to assess result of wound cultures, the nursing intervention (95,60 %) compared with that before the 'nursing intervention (24.6%).