Obesity has reached epidemic proportions globally, with associated increased risks of coronary heart disease, hypertension and type 2 diabetes mellitus. It is essential that nurses be knowledgeable regarding obesity prevention and health promotion. The aim of this study was to investigate the relation between obesity and triglycerides and blood glucose levels among University employees in Egypt and to compare these parameters in Lower and Upper Egypt. The study was conducted at different faculties at Lower (Banha, EI-Mansoura, Zagazig) and Upper (Assiut) Egypt universities. Data collection tools included a structured interview questionnaire form a physical assessment sheet and laboratory assessment of serum triglycerides and fasting blood sugar. Data collection lasted from February to May 2005. The results revealed that significantly more subjects in Lower Egypt had a family history of obesity (p