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Role of MRI in the diagnosis of adult traumatic and obstetric brachial plexus injury compared to intraoperative findings

Research Abstract
Background Brachial plexus injury occurs following birth trauma or adult trauma as well, surgical repair is important to regain upper limb function, and preoperative evaluation with MRI is important and considered the accurate and safe imaging modality. Thirty-seven patients with clinically suspected obstetric (15 patients) or adult traumatic (22 patients) brachial plexus injury were included in our study; all of them underwent MRI examination including T1WI, T2WI, STIR, DWIBS, 3D STIR SPACE, and MR myelography sequences. Results In obstetric cases, MRI sensitivity, specificity, and accuracy for preganglionic injury were 63%, 89%, and 82%, respectively, while for postganglionic lesions, MRI sensitivity, specificity, and accuracy were 60%, 99%, and 95%, respectively. In adult cases, MRI sensitivity, specificity, and accuracy for preganglionic injury were 96%, 95%, and 95% respectively, while for postganglionic injury, MRI sensitivity, specificity, and accuracy were 60%, 100%, and 99%, respectively. Conclusion MRI represents a safe, non-invasive, diagnostic modality having the multiplanar capability and better soft tissue characterization.
Research Authors
Doria Mohammed Gad, Mostafa Thabet Hussein, Nagham Nabil Mahmoud Omar, Mohamed Mostafa Kotb, Mohamed Abdel-Tawab & Hazem Abu Zeid Yousef
Research Journal
Egyptian Journal of Radiology and Nuclear Medicine
Research Pages
NULL
Research Publisher
springer
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Accumulation of B1-like B cells in transgenic mice overexpressing catalytically inactive RAG1in the periphery

Research Abstract
NULL
Research Authors
Ashraf E. Hassaballa, Victoria L. Palmer, Dirk K. Anderson, Michele D. Kassmeier, Vincent Nganga, Kevin W. Parks, Dustin Volkmer, Greg A. Perry, and Patrick C. Swanson
Research Journal
. Immunology. 2011 Dec; 134(4): 469-86.
Research Pages
469-486
Research Publisher
NULL
Research Rank
1
Research Vol
134(4)
Research Website
NULL
Research Year
2011

Value of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis

Research Abstract
Disease activity score 28 (DAS28) for rheumatoid arthritis (RA) is the commonly used DAS; it relies on clinical parameters that could be subjective. This work aimed to create a more accurate DAS for RA and assess its validity. Patients and Methods: The study included 98 RA patients and 53 matched controls; they were interviewed, clinically examined, their visual analogue scales (VAS) were reported, and then blood samples were withdrawn for erythrocyte sedimentation rate (ESR), complete blood count (CBC), and C-reactive protein (CRP). Platelet indices (PIs) were obtained from the CBC including Plt (platelet count), mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT). DAS28 was calculated for each patient using RheumaHelper mobile software. Minitab Statistical Package® and SPSS v20 software were used for data analysis. Results and Conclusions: Results revealed perfect matching between patients and controls as regarding age and gender. ESR, CRP and PDW were significantly higher in patients than controls; also positive correlations were detected among these variables. A new DAS for RA was developed; ESR, CRP, PDW and MPV were the components for this index. Further analyses showed that this new score was significantly higher in patients than controls and correlated with DAS28 of the patients. Furthermore the new score could identify RA patients from healthy subjects (cut off value − 0.79) and stratified RA patients according to their disease activity into low, intermediate, high, or in remission. Conclusively, we developed a more precise, easily obtained new DAS for RA. This new DAS has both diagnostic/prognostic values in patients with RA.
Research Authors
Safaa AA Khaled, Eman NasrEldin, Yasmine S Makarem, Hamdy FF Mahmoud
Research Journal
Journal of Inflammation Research
Research Pages
pp. 595-606
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 13
Research Website
NULL
Research Year
2020

Value of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis

Research Abstract
Disease activity score 28 (DAS28) for rheumatoid arthritis (RA) is the commonly used DAS; it relies on clinical parameters that could be subjective. This work aimed to create a more accurate DAS for RA and assess its validity. Patients and Methods: The study included 98 RA patients and 53 matched controls; they were interviewed, clinically examined, their visual analogue scales (VAS) were reported, and then blood samples were withdrawn for erythrocyte sedimentation rate (ESR), complete blood count (CBC), and C-reactive protein (CRP). Platelet indices (PIs) were obtained from the CBC including Plt (platelet count), mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT). DAS28 was calculated for each patient using RheumaHelper mobile software. Minitab Statistical Package® and SPSS v20 software were used for data analysis. Results and Conclusions: Results revealed perfect matching between patients and controls as regarding age and gender. ESR, CRP and PDW were significantly higher in patients than controls; also positive correlations were detected among these variables. A new DAS for RA was developed; ESR, CRP, PDW and MPV were the components for this index. Further analyses showed that this new score was significantly higher in patients than controls and correlated with DAS28 of the patients. Furthermore the new score could identify RA patients from healthy subjects (cut off value − 0.79) and stratified RA patients according to their disease activity into low, intermediate, high, or in remission. Conclusively, we developed a more precise, easily obtained new DAS for RA. This new DAS has both diagnostic/prognostic values in patients with RA.
Research Authors
Safaa AA Khaled, Eman NasrEldin, Yasmine S Makarem, Hamdy FF Mahmoud
Research Journal
Journal of Inflammation Research
Research Pages
pp. 595-606
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 13
Research Website
NULL
Research Year
2020

Value of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis

Research Abstract
Disease activity score 28 (DAS28) for rheumatoid arthritis (RA) is the commonly used DAS; it relies on clinical parameters that could be subjective. This work aimed to create a more accurate DAS for RA and assess its validity. Patients and Methods: The study included 98 RA patients and 53 matched controls; they were interviewed, clinically examined, their visual analogue scales (VAS) were reported, and then blood samples were withdrawn for erythrocyte sedimentation rate (ESR), complete blood count (CBC), and C-reactive protein (CRP). Platelet indices (PIs) were obtained from the CBC including Plt (platelet count), mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT). DAS28 was calculated for each patient using RheumaHelper mobile software. Minitab Statistical Package® and SPSS v20 software were used for data analysis. Results and Conclusions: Results revealed perfect matching between patients and controls as regarding age and gender. ESR, CRP and PDW were significantly higher in patients than controls; also positive correlations were detected among these variables. A new DAS for RA was developed; ESR, CRP, PDW and MPV were the components for this index. Further analyses showed that this new score was significantly higher in patients than controls and correlated with DAS28 of the patients. Furthermore the new score could identify RA patients from healthy subjects (cut off value − 0.79) and stratified RA patients according to their disease activity into low, intermediate, high, or in remission. Conclusively, we developed a more precise, easily obtained new DAS for RA. This new DAS has both diagnostic/prognostic values in patients with RA.
Research Authors
Safaa AA Khaled, Eman NasrEldin, Yasmine S Makarem, Hamdy FF Mahmoud
Research Department
Research Journal
Journal of Inflammation Research
Research Pages
pp. 595-606
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 13
Research Website
NULL
Research Year
2020

Value of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis

Research Abstract
Disease activity score 28 (DAS28) for rheumatoid arthritis (RA) is the commonly used DAS; it relies on clinical parameters that could be subjective. This work aimed to create a more accurate DAS for RA and assess its validity. Patients and Methods: The study included 98 RA patients and 53 matched controls; they were interviewed, clinically examined, their visual analogue scales (VAS) were reported, and then blood samples were withdrawn for erythrocyte sedimentation rate (ESR), complete blood count (CBC), and C-reactive protein (CRP). Platelet indices (PIs) were obtained from the CBC including Plt (platelet count), mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT). DAS28 was calculated for each patient using RheumaHelper mobile software. Minitab Statistical Package® and SPSS v20 software were used for data analysis. Results and Conclusions: Results revealed perfect matching between patients and controls as regarding age and gender. ESR, CRP and PDW were significantly higher in patients than controls; also positive correlations were detected among these variables. A new DAS for RA was developed; ESR, CRP, PDW and MPV were the components for this index. Further analyses showed that this new score was significantly higher in patients than controls and correlated with DAS28 of the patients. Furthermore the new score could identify RA patients from healthy subjects (cut off value − 0.79) and stratified RA patients according to their disease activity into low, intermediate, high, or in remission. Conclusively, we developed a more precise, easily obtained new DAS for RA. This new DAS has both diagnostic/prognostic values in patients with RA.
Research Authors
Safaa AA Khaled, Eman NasrEldin, Yasmine S Makarem, Hamdy FF Mahmoud
Research Journal
Journal of Inflammation Research
Research Pages
pp. 595-606
Research Publisher
NULL
Research Rank
1
Research Vol
Vol. 13
Research Website
NULL
Research Year
2020

Use of fractional co2 laser in cleft lip scar. Does it make a difference?

Research Abstract
NULL
Research Authors
ط/ محمد شداد راتب محمد
د/ وجدي محمد علي
د/ غلام فياز قدير
أد/ محمد الشاذلي
Research Department
Research Journal
Annals of plastic surgery
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Use of fractional co2 laser in cleft lip scar. Does it make a difference?

Research Abstract
NULL
Research Authors
ط/ محمد شداد راتب محمد
د/ وجدي محمد علي
د/ غلام فياز قدير
أد/ محمد الشاذلي
Research Department
Research Journal
Annals of plastic surgery
Research Member
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Use of fractional co2 laser in cleft lip scar. Does it make a difference?

Research Abstract
NULL
Research Authors
ط/ محمد شداد راتب محمد
د/ وجدي محمد علي
د/ غلام فياز قدير
أد/ محمد الشاذلي
Research Department
Research Journal
Annals of plastic surgery
Research Member
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Superiority of cardiac magnetic resonance imaging over echocardiography in early detection of subclinical cardiac abnormalities in systemic lupus erythematosus patients

Research Abstract
Background Cardiovascular disease (CVD) has become increasingly recognized as a cause of mortality, especially in patients with long-standing systemic lupus erythematosus (SLE). Aim of the work To detect subclinical cardiac involvement and its relation to clinical characteristics, disease activity and damage. Patients and methods Transthoracic echocardiography (TTE) was performed in 36 SLE patients. Cardiac magnetic resonance (CMR) sections were obtained. T1-weighted inversion recovery scout images were obtained after injection of gadolinium. Results Thirty-six patients were included with a mean age of 32.4 ± 8.5 years; 35 females and 1 male; with disease duration of 7.9 ± 5 years. The frequent cardiac presentations on TTE were tricuspid regurgitation (TR) (41.6%), mitral regurgitation (MR) (36.1%), mitral thickening (25%), early diastolic mitral flow/mitral flow during atrial contraction (E/A) 1 (19.4%). The most frequent cardiac presentations by CMR were MR (25%), pericarditis (25%), mitral thickening (13.9%), TR (13.9%), myocarditis (8.3). Neither SLE Disease Activity Index (SLEDAI) nor Systemic Lupus International Collaborating Clinics (SLICC) damage index, high- sensitivity-C reactive protein (hsCRP), C3 and C4 levels were significantly correlated with the ejection fraction (EF) by CMR. There was significant negative correlation between disease duration and EF by CMR (r = −0.36, p = 0.03). Using multiple regression, EF by CMR was strongly predicted by disease duration (p = 0.025). The analysis of EF and MR fraction by CMR and TTE showed acceptable moderate agreement. CMR and TTE showed 83.3% agreement in the detection of pericarditis. Conclusion CMR is superior to echocardiography in detection of subclinical abnormalities in SLE.
Research Authors
Samar H. Goma, Naima M. Mostafa, Nadia M Ismail, Salma Taha, Zeinab A. Abd Elhameed, Shimaa Khidr, Maha Abdelrahman
Research Journal
The Egyptian Rheumatologist
Research Pages
NULL
Research Publisher
Elsevier
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020
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