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A retrospective cohort study evaluating efficacy in high‐risk patients with chronic lower extremity ulcers treated with negative pressure wound therapy‏

Research Authors
M Yao, M Fabbi, H Hayashi, N Park, K Attala, G Gu, MA French, VR Driver‏
Research Date
Research Department
Research Journal
International wound journal 11 (5), 483-488‏

A pilot study evaluating non‐contact low‐frequency ultrasound and underlying molecular mechanism on diabetic foot ulcers‏

Research Authors
M Yao, H Hasturk, A Kantarci, G Gu, S Garcia‐Lavin, M Fabbi, N Park, ...‏
Research Date
Research Department
Research Journal
International wound journal 11 (6), 586-593‏

Analyzing central-line associated bloodstream infection prevention bundles in 22 countries: The results of ID-IRI survey

Research Abstract

Background

Because central line-associated bloodstream infections (CLABSIs) are a significant complication of central venous access, it is critical to prevent CLABSIs through the use of central line bundles. The purpose of this study was to take a snapshot of central venous access bundles in various countries.

Methods

The participants in intensive care units (ICUs) completed a questionnaire that included information about the health center, infection control procedures, and central line maintenance. The countries were divided into 2 groups: those with a low or low-middle income and those with an upper-middle or high income.

Results

Forty-three participants from 22 countries (46 hospitals, 85 ICUs) responded to the survey. Eight (17.4%) hospitals had no surveillance system for CLABSI. Approximately 7.1 % (n = 6) ICUs had no CLABSI bundle. Twenty ICUs (23.5%) had no dedicated checklist. The percentage of …

Research Authors
Ilker Devrim, Hakan Erdem, Amani El-Kholy, Abdullah Almohaizeie, Mateja Logar, Bilal Ahmad Rahimi, Fatma Amer, Sevil Alkan-Ceviker, Meliha Cagla Sonmezer, Maya Belitova, Jamal Wadi Al-Ramahi, Natalia Pshenichnaya, Maha Ali Gad, Lurdes Santos, Reham Khedr,
Research Date
Research Journal
American journal of infection control
Research Pages
1327-1332
Research Publisher
Mosby
Research Year
2022

Predictors of three months mortality after endovascular mechanical thrombectomy for acute ischemic stroke

Research Abstract

Objective

This study aims to determine predictive factors of mortality within 3 months after mechanical thrombectomy (MT) for patients with acute ischemic stroke (AIS).

Methods

This prospective cohort study was carried out at Assiut University stroke center in collaboration with Ain Shams University Egypt. Forty-four patients with anterior circulation AIS underwent MT between the first of January 2020 to the end of December 2020. They were evaluated for detection of death rates and identification of risks of 3-month mortality after MT.

Results

This study comprised 44 patients (52.3% male) with a mean age of 64.3 years. The mean time from onset to femoral arterial puncture was 304.1 min. The mean Alberta Stroke Program Early CT Score (ASPECTS) and National Institutes of Health Stroke Scale (NIHSS) score were 9.3 and 19.2, respectively. The 3-month mortality rate was 13.6%. Univariate analyses found that higher

Research Authors
Wafaa M Farghaly, Mohamed A Ahmed, Ahmed El-Bassiouny, Ahmed A Hamed, Ghaydaa A Shehata
Research Date
Research Journal
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Research Year
2022

Neurological manifestations in a cohort of Egyptian patients with COVID-19: a prospective, multicenter, observational study

Research Abstract

Background

The COVID-19 pandemic has reached over 276 million people globally with 5.3 million deaths as of 22nd December 2021. COVID-19-associated acute and long-term neurological manifestations are well recognized. The exact profile and the timing of neurological events in relation to the onset of infection are worth exploring. The aim of the current body of work was to determine the frequency, pattern, and temporal profile of neurological manifestations in a cohort of Egyptian patients with confirmed COVID-19 infection.

Methods

This was a prospective study conducted on 582 hospitalized COVID-19 patients within the first two weeks of the diagnosis of COVID-19 to detect any specific or non-specific neurological events.

Results

The patients’ mean (SD) age was 46.74 (17.26) years, and 340 (58.42%) patients were females. The most commonly encountered COVID-19 symptoms were fever (90.72%), cough (82.99%), and fatigue (76.98%). Neurological events (NE) detected in 283 patients (48.63%) and were significantly associated with a severe COVID-19 at the onset (OR: 3.13; 95% CI: 2.18–4.51; p < 0.0001) and with a higher mortality (OR: 2.56; 95% CI: 1.48–5.46; p = 0.019). The most frequently reported NEs were headaches (n = 167) and myalgias (n = 126). Neurological syndromes included stroke (n = 14), encephalitis (n = 12), encephalopathy (n = 11), transverse myelitis (n = 6) and Guillain-Barré syndrome (n = 4).

Conclusions

Neurological involvement is common (48.63%) in COVID-19 patients within the first two weeks of the illness. This includes neurological symptoms such as anosmia, headaches, as well as a constellation …

Research Authors
Doaa A Mekkawy, Sherif Hamdy, Maged Abdel-Naseer, Hatem S Shehata, Ahmed Al Halfawy, Nevin M Shalaby, Ghaydaa A Shehata, Anwar M Ali, Alaa Elmazny, Sandra M Ahmed, Jumana H Ismail, Aml Ibraheim, Hoda M Abdel-Hamid, Rehab Magdy, Younan Kabara Ayoub, Ahmed
Research Date
Research Journal
Brain Sciences
Research Pages
74
Research Publisher
MDPI
Research Year
2022

Vitamin D3 status and polymorphisms of vitamin D receptor genes among cohort of Egyptian children with autism

Research Authors
Nagwan Mohammed HASSAN, Ghaydaa Ahmed SHEHATA, Ahmed El-Abd AHMED, Samer A. EL-SAWY, Amal M. TOHAMY, Hala M. SAKHR, Ali Helmi BAKRI, Hebatallah ABDELLATIF, Hesham H. AMEEN, Ahmed Alamir Mahmoud ABDALLAH
Research Date
Research Journal
Gazz Med Ital - Arch Sci Med
Research Year
2022

Vaccine hesitancy and refusal among parents: An international ID-IRI survey

Research Abstract

Introduction: Although vaccines are the safest and most effective means to prevent and control infectious diseases, the increasing rate of vaccine hesitancy and refusal (VHR) has become a worldwide concern. We aimed to find opinions of parents on vaccinating their children and contribute to available literature in order to support the fight against vaccine refusal by investigating the reasons for VHR on a global scale.

Methodology: In this international cross-sectional multicenter study conducted by the Infectious Diseases International Research Initiative (ID-IRI), a questionnaire consisting of 20 questions was used to determine parents’ attitudes towards vaccination of their children.

Results: Four thousand and twenty-nine (4,029) parents were included in the study and 2,863 (78.1%) were females. The overall VHR rate of the parents was found to be 13.7%. Nineteen-point three percent (19.3%) of the parents did not fully comply with the vaccination programs. The VHR rate was higher in high-income (HI) countries. Our study has shown that parents with disabled children and immunocompromised children, with low education levels, and those who use social media networks as sources of information for childhood immunizations had higher VHR rates (p< 0.05 for all).

Conclusions: Seemingly all factors leading to VHR are related to training of the community and the sources of training. Thus, it is necessary to develop strategies at a global level and provide reliable knowledge to combat VHR.

Research Authors
Yakup Cag, Mohammad Emad Al Madadha, Handan Ankarali, Yasemin Cag, Kubra Demir Onder, Aysegul Seremet-Keskin, Filiz Kizilates, Ghaydaa Shehata, Handan Alay, Sevil Alkan-Ceviker, Fatma Yilmaz-Karadag, Meliha Cagla-Sonmezer, Manar Ezzelarab Ramadan, Dumitru
Research Date
Research Journal
The Journal of Infection in Developing Countries
Research Pages
1081-1088
Research Year
2022
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