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Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.

Research Authors
Ola M. Omran, MD, PhD1 and Mostafa thabet, MD, PhD2
Research Department
Research Journal
Ultrastruct Pathol.
Research Pages
pp. 108-16
Research Rank
2
Research Vol
Vol. 36 - No.2
Research Year
2012

Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.

Research Authors
Ola M. Omran, MD, PhD1 and Mostafa thabet, MD, PhD2
Research Department
Research Journal
Ultrastruct Pathol.
Research Member
Research Pages
pp. 108-16
Research Rank
2
Research Vol
Vol. 36 - No.2
Research Year
2012

Role of Chlamydia Trachomatis and Genital Tuberculosis in Primary Infertility

Research Abstract
Pelvic inflammatory disease (PID) is the most common cause of tubal disease as a cause of primary infertility. This study aimed to assess the rate of M. tuberculosis and C. trachomatis infections in patients with tubal factor infertility. Methods: One hundred twenty women with primary infertility and abnormal Hysterosalpingography were enrolled as a studied group and 60 infertile women with polycystic ovary as the only cause of infertility and normal Hysterosalpingography as a control group. Laparoscopy was performed and biopsy was taken for histopathological study. ELISA detection for Mycobacterium tuberculosis and C. trachomatis IgG antibodies was done. PCR for detection mpt64 gene of M. tuberculosis and C. trachomatis plasmid DNA also were done. Results: IgG for M.tuberculosis were +ve in 96 cases (80%) of the studied group and it was +ve in 46 cases (76.7%) of the control group with no statistical significant difference. Only 17 cases (18.9%) of the study group showed +ve results for mpt64 gene of M. tuberculosis. IgG for C. trachomatis were +ve in 43 cases (47.8%) of the study group and it was +ve in 5 cases (13.3%) of the control group with height statistical significant difference. The +ve titers range from >5 IU to 40 IU. PCR was done for Chlamydia in peritoneal fluid only 5 cases (5.6%) of the studied group was +ve for chlamydia PCR and it was –ve in all control groups. Conclusions: PCR for mpt64 gene o f M. tuberculosis plays an important role in diagnosis of genital tuberculosis. Screening of infertile women for C. trachomatis is recommended in the first year of infertility, so that early therapeutic intervention can be instituted to allow women to conceive naturally.
Research Authors
Madiha M El –Attar, Safwat Abdel-Rady*, Salma Abdel-Hamed*, Hebat-Allah G Rashed**, Hossam Thabet*
Research Journal
مؤتمر أمراض النساء والخصوبة والمنعقد فى اسطنبول
Research Rank
2
Research Year
2013

Role of Chlamydia Trachomatis and Genital Tuberculosis in Primary Infertility

Research Abstract
Pelvic inflammatory disease (PID) is the most common cause of tubal disease as a cause of primary infertility. This study aimed to assess the rate of M. tuberculosis and C. trachomatis infections in patients with tubal factor infertility. Methods: One hundred twenty women with primary infertility and abnormal Hysterosalpingography were enrolled as a studied group and 60 infertile women with polycystic ovary as the only cause of infertility and normal Hysterosalpingography as a control group. Laparoscopy was performed and biopsy was taken for histopathological study. ELISA detection for Mycobacterium tuberculosis and C. trachomatis IgG antibodies was done. PCR for detection mpt64 gene of M. tuberculosis and C. trachomatis plasmid DNA also were done. Results: IgG for M.tuberculosis were +ve in 96 cases (80%) of the studied group and it was +ve in 46 cases (76.7%) of the control group with no statistical significant difference. Only 17 cases (18.9%) of the study group showed +ve results for mpt64 gene of M. tuberculosis. IgG for C. trachomatis were +ve in 43 cases (47.8%) of the study group and it was +ve in 5 cases (13.3%) of the control group with height statistical significant difference. The +ve titers range from >5 IU to 40 IU. PCR was done for Chlamydia in peritoneal fluid only 5 cases (5.6%) of the studied group was +ve for chlamydia PCR and it was –ve in all control groups. Conclusions: PCR for mpt64 gene o f M. tuberculosis plays an important role in diagnosis of genital tuberculosis. Screening of infertile women for C. trachomatis is recommended in the first year of infertility, so that early therapeutic intervention can be instituted to allow women to conceive naturally.
Research Authors
Madiha M El –Attar, Safwat Abdel-Rady*, Salma Abdel-Hamed*, Hebat-Allah G Rashed**, Hossam Thabet*
Research Journal
مؤتمر أمراض النساء والخصوبة والمنعقد فى اسطنبول
Research Rank
2
Research Year
2013

Role of Chlamydia Trachomatis and Genital Tuberculosis in Primary Infertility

Research Abstract
Pelvic inflammatory disease (PID) is the most common cause of tubal disease as a cause of primary infertility. This study aimed to assess the rate of M. tuberculosis and C. trachomatis infections in patients with tubal factor infertility. Methods: One hundred twenty women with primary infertility and abnormal Hysterosalpingography were enrolled as a studied group and 60 infertile women with polycystic ovary as the only cause of infertility and normal Hysterosalpingography as a control group. Laparoscopy was performed and biopsy was taken for histopathological study. ELISA detection for Mycobacterium tuberculosis and C. trachomatis IgG antibodies was done. PCR for detection mpt64 gene of M. tuberculosis and C. trachomatis plasmid DNA also were done. Results: IgG for M.tuberculosis were +ve in 96 cases (80%) of the studied group and it was +ve in 46 cases (76.7%) of the control group with no statistical significant difference. Only 17 cases (18.9%) of the study group showed +ve results for mpt64 gene of M. tuberculosis. IgG for C. trachomatis were +ve in 43 cases (47.8%) of the study group and it was +ve in 5 cases (13.3%) of the control group with height statistical significant difference. The +ve titers range from >5 IU to 40 IU. PCR was done for Chlamydia in peritoneal fluid only 5 cases (5.6%) of the studied group was +ve for chlamydia PCR and it was –ve in all control groups. Conclusions: PCR for mpt64 gene o f M. tuberculosis plays an important role in diagnosis of genital tuberculosis. Screening of infertile women for C. trachomatis is recommended in the first year of infertility, so that early therapeutic intervention can be instituted to allow women to conceive naturally.
Research Authors
Madiha M El –Attar, Safwat Abdel-Rady*, Salma Abdel-Hamed*, Hebat-Allah G Rashed**, Hossam Thabet*
Research Journal
مؤتمر أمراض النساء والخصوبة والمنعقد فى اسطنبول
Research Rank
2
Research Year
2013

Role of Chlamydia Trachomatis and Genital Tuberculosis in Primary Infertility

Research Abstract
Pelvic inflammatory disease (PID) is the most common cause of tubal disease as a cause of primary infertility. This study aimed to assess the rate of M. tuberculosis and C. trachomatis infections in patients with tubal factor infertility. Methods: One hundred twenty women with primary infertility and abnormal Hysterosalpingography were enrolled as a studied group and 60 infertile women with polycystic ovary as the only cause of infertility and normal Hysterosalpingography as a control group. Laparoscopy was performed and biopsy was taken for histopathological study. ELISA detection for Mycobacterium tuberculosis and C. trachomatis IgG antibodies was done. PCR for detection mpt64 gene of M. tuberculosis and C. trachomatis plasmid DNA also were done. Results: IgG for M.tuberculosis were +ve in 96 cases (80%) of the studied group and it was +ve in 46 cases (76.7%) of the control group with no statistical significant difference. Only 17 cases (18.9%) of the study group showed +ve results for mpt64 gene of M. tuberculosis. IgG for C. trachomatis were +ve in 43 cases (47.8%) of the study group and it was +ve in 5 cases (13.3%) of the control group with height statistical significant difference. The +ve titers range from >5 IU to 40 IU. PCR was done for Chlamydia in peritoneal fluid only 5 cases (5.6%) of the studied group was +ve for chlamydia PCR and it was –ve in all control groups. Conclusions: PCR for mpt64 gene o f M. tuberculosis plays an important role in diagnosis of genital tuberculosis. Screening of infertile women for C. trachomatis is recommended in the first year of infertility, so that early therapeutic intervention can be instituted to allow women to conceive naturally.
Research Authors
Madiha M El –Attar, Safwat Abdel-Rady*, Salma Abdel-Hamed*, Hebat-Allah G Rashed**, Hossam Thabet*
Research Journal
مؤتمر أمراض النساء والخصوبة والمنعقد فى اسطنبول
Research Rank
2
Research Year
2013

A community-based epidemiological study of
peripheral neuropathies in Assiut, Egypt

Research Abstract
There is very little published information about the prevalence, patterns, and predictors of peripheral neuropathies. The current study is a community-based survey was conducted in the Assiut Governorate to estimate their prevalence and clinical profile. Material and methods: A door-to-door study was carried out on 42 223 persons from rural and urban communities in the Assiut Governorate, Egypt. There were 13 288 (31.5%) subjects from the urban and 28 935 (68.5%) from the rural area. All subjects filled in a questionnaire designed specifically for diagnosis of peripheral neuropathy. Positive cases were then given a complete medical and neurological examination, routine laboratory tests, neurophysiology, and neuroimaging (magnetic resonance). Results: The crude prevalence rate (CPR) of peripheral neuropathy was 3181/100 000 inhabitants. There was a significantly higher prevalence in the rural compared with the urban population (3795 versus 1844/ 100 000) and in females than males (4473 versus 1943/100 000; P,0.001 for both). The most common type reported was entrapment neuropathy (736 cases with CPR of 1743/100 000), particularly carpal tunnel syndrome (1686/100 000). Diabetic neuropathy was the most common non-compressive neuropathy with a CPR of 649/100 000. Type II diabetes was recorded in 241 patients with a CPR of 571/100 000. Compressive radiculopathy had a crude prevalence of 358/100 000; traumatic and iatrogenic radiculopathy had a prevalence rate of 149/100 000. Less common conditions were: uremic neuropathy (21/ 100 000) hepatic neuropathy (14/100 000), Bell’s palsy (28/100 000), Guillian–Barre’ syndrome (12/ 100 000), chronic inflammatory demyelinating polyneuropathy (12/100 000), hereditary sensory motor neuropathy (12/100 000), and idiopathic neuropathy (92/100 000). Conclusion: The overall prevalence of peripheral neuropathies was high in comparison to other studies. Entrapment neuropathy, diabetic neuropathy, and spondylotic radiculopathy were the most common. Overall, the prevalence of peripheral neuropathy was higher in the rural than in the urban population.
Research Authors
Mahmoud R. Kandil, Esam S. Darwish, Eman M. Khedr, Mahmoud M. Sabry,
Mohamed A. Abdulah
Research Journal
Neurological Research
Research Rank
1
Research Year
2012
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