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A community based epidemiological study of epilepsy in Assiut Governorate/Egypt

Research Abstract
Background: The aim of the study was to estimate the prevalence of different types of epilepsy and their possible risk factors in the region of the Assiut Governorate/Egypt. Material and methods: A community based study with random sampling of 7 districts, involving 6498 inhabitants. Out of this sample, 578 dropped out leaving 3066 males (51.8%) and 2854 females (48.2%). There were 3660 (61.8%) urban residents and 2260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire for epilepsy, and then referred to the hospital to be re-evaluated by a qualified neurologist and with electroencephalography (EEG) and computed tomography of the brain (CT). Results: Seventy-five cases were diagnosed with epilepsy giving an overall the crude lifetime prevalence rate (CPR) for epilepsy of 12.67/1000 (95% CI: 9.8—15.54). The active prevalence rate was 9.3/1000 and the incidence rate was 1.5/1000 (95% confidence interval: 0.53—2.51). Fifty-six cases (75%) had idiopathic epilepsy (CPR 9.5/1000). Symptomatic epilepsy was recorded in 19 (25%) cases (CPR 3.2/1000). Generalized seizures were more common (CPR 6.75/1000) than partial seizures (CPR 2.5/1000). The prevalence rate of partial seizures evolving to secondary generalization was 0.84/1000 while simple partial and complex partial seizures had CPR 1.4/1000 and 0.34/1000, respectively. The CPR of mixed seizures was 0.17/1000. Epilepsy was slightly but not significantly more common among males than females (CPR of 14.4 and 10.9 per 1000 population, respectively). The CPR was higher in rural than urban populations (17.7/1000, with 95% CI 12.2—23.18 and 9.56/1000, with 95% CI: 6.39—12.7, respectively) and in the illiterate group than the literate population (12.02/1000 and 9.94/1000, respectively). The highest prevalence rate was recorded in the early and late childhood period (69.78/100,000 and 43.78/100,000, respectively). Prenatal insults and infection represented major causes of symptomatic epilepsy.
Research Authors
Eman M. Khedr , Ola A. Shawky , Mohamed A. Ahmed ,
Noha Abo Elfetoh , Ghada Al Attar , Anwar M. Ali , Mahmoud R. Kandil , Hassan Farweez
Research Journal
Epilepsy Research
Research Pages
PP.294-302
Research Rank
1
Research Vol
Vol.103, No.2-3
Research Year
2013

A community based epidemiological study of epilepsy in Assiut Governorate/Egypt

Research Abstract
Background: The aim of the study was to estimate the prevalence of different types of epilepsy and their possible risk factors in the region of the Assiut Governorate/Egypt. Material and methods: A community based study with random sampling of 7 districts, involving 6498 inhabitants. Out of this sample, 578 dropped out leaving 3066 males (51.8%) and 2854 females (48.2%). There were 3660 (61.8%) urban residents and 2260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire for epilepsy, and then referred to the hospital to be re-evaluated by a qualified neurologist and with electroencephalography (EEG) and computed tomography of the brain (CT). Results: Seventy-five cases were diagnosed with epilepsy giving an overall the crude lifetime prevalence rate (CPR) for epilepsy of 12.67/1000 (95% CI: 9.8—15.54). The active prevalence rate was 9.3/1000 and the incidence rate was 1.5/1000 (95% confidence interval: 0.53—2.51). Fifty-six cases (75%) had idiopathic epilepsy (CPR 9.5/1000). Symptomatic epilepsy was recorded in 19 (25%) cases (CPR 3.2/1000). Generalized seizures were more common (CPR 6.75/1000) than partial seizures (CPR 2.5/1000). The prevalence rate of partial seizures evolving to secondary generalization was 0.84/1000 while simple partial and complex partial seizures had CPR 1.4/1000 and 0.34/1000, respectively. The CPR of mixed seizures was 0.17/1000. Epilepsy was slightly but not significantly more common among males than females (CPR of 14.4 and 10.9 per 1000 population, respectively). The CPR was higher in rural than urban populations (17.7/1000, with 95% CI 12.2—23.18 and 9.56/1000, with 95% CI: 6.39—12.7, respectively) and in the illiterate group than the literate population (12.02/1000 and 9.94/1000, respectively). The highest prevalence rate was recorded in the early and late childhood period (69.78/100,000 and 43.78/100,000, respectively). Prenatal insults and infection represented major causes of symptomatic epilepsy.
Research Authors
Eman M. Khedr , Ola A. Shawky , Mohamed A. Ahmed ,
Noha Abo Elfetoh , Ghada Al Attar , Anwar M. Ali , Mahmoud R. Kandil , Hassan Farweez
Research Journal
Epilepsy Research
Research Pages
PP.294-302
Research Rank
1
Research Vol
Vol.103, No.2-3
Research Year
2013

A community based epidemiological study of epilepsy in Assiut Governorate/Egypt

Research Abstract
Background: The aim of the study was to estimate the prevalence of different types of epilepsy and their possible risk factors in the region of the Assiut Governorate/Egypt. Material and methods: A community based study with random sampling of 7 districts, involving 6498 inhabitants. Out of this sample, 578 dropped out leaving 3066 males (51.8%) and 2854 females (48.2%). There were 3660 (61.8%) urban residents and 2260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire for epilepsy, and then referred to the hospital to be re-evaluated by a qualified neurologist and with electroencephalography (EEG) and computed tomography of the brain (CT). Results: Seventy-five cases were diagnosed with epilepsy giving an overall the crude lifetime prevalence rate (CPR) for epilepsy of 12.67/1000 (95% CI: 9.8—15.54). The active prevalence rate was 9.3/1000 and the incidence rate was 1.5/1000 (95% confidence interval: 0.53—2.51). Fifty-six cases (75%) had idiopathic epilepsy (CPR 9.5/1000). Symptomatic epilepsy was recorded in 19 (25%) cases (CPR 3.2/1000). Generalized seizures were more common (CPR 6.75/1000) than partial seizures (CPR 2.5/1000). The prevalence rate of partial seizures evolving to secondary generalization was 0.84/1000 while simple partial and complex partial seizures had CPR 1.4/1000 and 0.34/1000, respectively. The CPR of mixed seizures was 0.17/1000. Epilepsy was slightly but not significantly more common among males than females (CPR of 14.4 and 10.9 per 1000 population, respectively). The CPR was higher in rural than urban populations (17.7/1000, with 95% CI 12.2—23.18 and 9.56/1000, with 95% CI: 6.39—12.7, respectively) and in the illiterate group than the literate population (12.02/1000 and 9.94/1000, respectively). The highest prevalence rate was recorded in the early and late childhood period (69.78/100,000 and 43.78/100,000, respectively). Prenatal insults and infection represented major causes of symptomatic epilepsy.
Research Authors
Eman M. Khedr , Ola A. Shawky , Mohamed A. Ahmed ,
Noha Abo Elfetoh , Ghada Al Attar , Anwar M. Ali , Mahmoud R. Kandil , Hassan Farweez
Research Journal
Epilepsy Research
Research Pages
PP.294-302
Research Rank
1
Research Vol
Vol.103, No.2-3
Research Year
2013

A community based epidemiological study of epilepsy in Assiut Governorate/Egypt

Research Abstract
Background: The aim of the study was to estimate the prevalence of different types of epilepsy and their possible risk factors in the region of the Assiut Governorate/Egypt. Material and methods: A community based study with random sampling of 7 districts, involving 6498 inhabitants. Out of this sample, 578 dropped out leaving 3066 males (51.8%) and 2854 females (48.2%). There were 3660 (61.8%) urban residents and 2260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire for epilepsy, and then referred to the hospital to be re-evaluated by a qualified neurologist and with electroencephalography (EEG) and computed tomography of the brain (CT). Results: Seventy-five cases were diagnosed with epilepsy giving an overall the crude lifetime prevalence rate (CPR) for epilepsy of 12.67/1000 (95% CI: 9.8—15.54). The active prevalence rate was 9.3/1000 and the incidence rate was 1.5/1000 (95% confidence interval: 0.53—2.51). Fifty-six cases (75%) had idiopathic epilepsy (CPR 9.5/1000). Symptomatic epilepsy was recorded in 19 (25%) cases (CPR 3.2/1000). Generalized seizures were more common (CPR 6.75/1000) than partial seizures (CPR 2.5/1000). The prevalence rate of partial seizures evolving to secondary generalization was 0.84/1000 while simple partial and complex partial seizures had CPR 1.4/1000 and 0.34/1000, respectively. The CPR of mixed seizures was 0.17/1000. Epilepsy was slightly but not significantly more common among males than females (CPR of 14.4 and 10.9 per 1000 population, respectively). The CPR was higher in rural than urban populations (17.7/1000, with 95% CI 12.2—23.18 and 9.56/1000, with 95% CI: 6.39—12.7, respectively) and in the illiterate group than the literate population (12.02/1000 and 9.94/1000, respectively). The highest prevalence rate was recorded in the early and late childhood period (69.78/100,000 and 43.78/100,000, respectively). Prenatal insults and infection represented major causes of symptomatic epilepsy.
Research Authors
Eman M. Khedr , Ola A. Shawky , Mohamed A. Ahmed ,
Noha Abo Elfetoh , Ghada Al Attar , Anwar M. Ali , Mahmoud R. Kandil , Hassan Farweez
Research Journal
Epilepsy Research
Research Member
Research Pages
PP.294-302
Research Rank
1
Research Vol
Vol.103, No.2-3
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Member
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Member
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013

Epidemiological Study and Risk Factors of Stroke in Assiut Governorate, Egypt: Community-Based Study

Research Abstract
B a c k g r o u n d : Because there have been no epidemiological studies of stroke in Egypt, a community-based survey was conducted in the Assiut Governorate to estimate the prevalence and risk factors of stroke in our community.M e t h o d s : A three-phase door-to-door study was performed in which 6,498 participants were chosen by random sampling from 7 districts in Assiut (first phase). Out of this sample, 578 dropped out leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 (61.8%) urban residents and 2,260 (38.2%) from the rural community. In the second phase participants were screened using the questionnaire for stroke, while the third phase involved medical evaluation of all suspected cases, with diagnosis of stroke confirmed by evaluation of CT scans. The Mini Mental State Examination and Hamilton Depression Scale were evaluated for each patient. R e s u l t s : 65 participants were identified as positive on the survey questionnaire, but only 57 patients were found to have stroke, giving a crude prevalence rate of 963/100,000 inhabitants with an age-adjusted local prevalence rate of 699.2/100,000 and an age-adjusted prevalence relative to the standard world population of 980.9/100,000. The prevalence among males was higher than females (1174/100,000 vs. 736/100,000) with a ratio 1.7: 1. There was a significantly higher prevalence of ischemic (895/100,000) than hemorrhagic (68/100,000) stroke. Stroke prevalence was the same in rural and urban areas and in males and females. There was, however, a significantly higher prevalence in illiterate (2413/100,000) than literate participants (357/100,000). Forty-two patients (73.7%) had one or more risk factors for stroke, hypertension being the commonest (66%) and diabetes mellitus second (38.6%). Nine cases had poststroke dementia (15.8%) and 14 cases (24.6%) had mild depression. C o n c l u s i o n s : The overall prevalence rate of stroke is high, especially in older adults, men and illiterate individuals. A higher prevalence of ischemic than hemorrhagic stroke was recorded, with hypertension and diabetes mellitus being the commonest risk factors in our community.
Research Authors
Eman M. Khedr, Noha Abo Elfetoh, Ghada Al Attar, Mohamed A. Ahmed, Anwer M. Ali, Ahmed Hamdy, Mahmoud R. Kandil, Hassan Farweez.
Research Journal
Neuroepidemiology
Research Pages
PP.288–294
Research Rank
1
Research Vol
Vol.40,No.4
Research Year
2013
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