Prognostic Value of Accumulative Expression of COX-2 and p53 in Small and Diffuse Large B Cell Lymphoma

Research Abstract
Description Cyclooxygenase-2 (COX-2) plays an important role in carcinogenesis, which catalyzes the conversion of arachidonic acid into prostaglandins. P53 is a tumor suppressor gene that contributes to apoptosis and cell cycle control. There is functional interaction between p53 and COX-2, which lead to abrogation of apoptosis and progression of malignancy. To assess the relationship between COX-2, p53 expression and the clinicopathololgic features in SLL and DLBCL. We immunohistochemically examined the expression of COX-2 and p53 in non-neoplastic lymphoid cells, lymph nodal low-grade (50 cases of SLL), intermediate and high-grade lymphomas (100 cases of DLBCL) and their corresponding bone marrow specimens. The expression of COX-2 and p53 was absent in the in non-neoplastic lymphoid cells. In contrast, their expression values increased progressively with the advancing grade of lymphoma (p  …
Research Authors
Amen H. Zaky, Dalia Elsers, Rania Bakry, Mostafa Abdelwanis, Ola Nabih, Rania Hafez,& Mahmoud Rezk
Research Journal
Pathology & Oncology Research
Research Pages
1183-1190
Research Publisher
Springer
Research Rank
1
Research Vol
26-2
Research Website
NULL
Research Year
2020

Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways

Research Abstract
NULL
Research Authors
Basel A Abdel-Wahab, Fares EM Ali, Saad A Alkahtani, Ali M Alshabi, Mater H Mahnashi, Emad HM Hassanein
Research Department
Department of Pharmacology
Research Journal
Immunopharmacology and Immunotoxicology
Research Member
Basel Abdel-Naeem Abdel-Wahab Mohamed
Research Pages
1-11
Research Publisher
Taylor & Francis
Research Rank
1
Research Vol
8
Research Website
NULL
Research Year
2020

Expression and localization of estrogen receptors in human renal cell carcinoma and their clinical significance

Research Abstract
NULL
Research Authors
H.E. El-Deek, A.M. Ahmed, T.S. Hassan, A.M. Morsy
Research Department
Department of Pathology
Research Journal
International Journal of Clinical and Experimental Pathology
Research Member
Heba El-Deek Mohamed El-Sayed
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
11
Research Website
NULL
Research Year
2018

Stress response and antioxidant profile in Egyptian cows naturally infected with lumpy skin disease

Research Abstract
NULL
Research Authors
Khalil, NSA & Waly, HSA
Research Department
Department of Medical Physiology
Research Journal
J. Multidiscip. Sci.
Research Member
Nasser Sayed Abou Kalil Abdel Satr
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Haematotoxic and genotoxic potential of penconazole and copper nanoparticles on Redbelly Tilapia (Tilapia Zillii)

Research Abstract
NULL
Research Authors
Osman AGM, Elmileegy IMH, Farrag MMS, Said RE, Khalil NSA, El-Sawy MF, Ahmed ES
Research Department
Department of Medical Physiology
Research Journal
Open Access Journal of Agriculture Research
Research Member
Nasser Sayed Abou Kalil Abdel Satr
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2019

Haematotoxic and genotoxic potential of penconazole and copper nanoparticles on Redbelly Tilapia (Tilapia Zillii)

Research Abstract
NULL
Research Authors
Osman AGM, Elmileegy IMH, Farrag MMS, Said RE, Khalil NSA, El-Sawy MF, Ahmed ES
Research Department
Department of Medical Physiology
Research Journal
Open Access Journal of Agriculture Research
Research Member
Ibtisam Mohamed Hasan Ali Elmeligi
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2019

Effects of dietary supplementation of Spirulina platensis on the physiological parameters of Clarias gariepinus after exposure to food shortage stress

Research Abstract
NULL
Research Authors
Mustafa Ahmed Fawzy, Alaa El-Din Hamed Sayed, Nasser Sayed Abou Khalil
Research Department
Department of Medical Physiology
Research Journal
Health Sciences Research
Research Member
Nasser Sayed Abou Kalil Abdel Satr
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2017

Effects of dietary supplementation of Spirulina platensis on the physiological parameters of Clarias gariepinus after exposure to food shortage stress

Research Abstract
NULL
Research Authors
Mustafa Ahmed Fawzy, Alaa El-Din Hamed Sayed, Nasser Sayed Abou Khalil
Research Journal
Health Sciences Research
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2017

Effects of dietary supplementation of Spirulina platensis on the physiological parameters of Clarias gariepinus after exposure to food shortage stress

Research Abstract
NULL
Research Authors
Mustafa Ahmed Fawzy, Alaa El-Din Hamed Sayed, Nasser Sayed Abou Khalil
Research Journal
Health Sciences Research
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2017
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