The emergence of multi-drug resistant (MDR) strains and even pan drug resistant (PDR) strains is alarming. In this study, we studied the resistance pattern of E. coli pathogens recovered from patients with different infections in different hospitals in Minia, Egypt and the co-existence of different resistance determinants. E. coli was the most prevalent among patients suffering from urinary tract infections (62%), while they were the least isolated from eye infections (10%). High prevalence of MDR isolates was found (73%) associated with high ESBLs and MBLs production (89.4% and 64.8%, respectively). bla_TEM (80%) and bla_NDM (43%) were the most frequent ESBL and MBL, respectively. None of the isolates harbored bla_KPC and bla_OXA-48 carbapenemase like genes. Also, the fluoroquinolone modifying enzyme gene aac-(6′)-Ib-cr was detected in 25.2% of the isolates. More than one gene was found in 81% of the isolates. Azithromycin was one of the most effective antibiotics against MDR E. coli pathogens. The high MAR index of the isolates and the high prevalence of resistance genes, indicates an important public health concern and high-risk communities where antibiotics are abused.

Abstract
A single dose of zearalenone (10 ~g/g LBW) was injected intraperitoneally to Wistar Albino rats at the age of 50-100 days. The uterine acetyl cholinesterase enzyme was significantly increased in the treated animals compared to that in the controls. Therefore, zearalenone would be considered as an esterogenic effector for increasing the uterine acetyl cholinesterase which enhances uterine relaxation and subsequently improves
its function for pregnancy in prematured-animals. Unlike estradiol, it was interesting to find that the estrogenicity of zearalenone was increased by the moderating progesterone hormone. Moreover, it was revealed in this study that the injected dose of zearalenone
had no deleterious effects on the pregnant rats at 10-12 days period of gestation. The harmful effects of zearalenone on pregnant animals cited in the literature (11, 13, 19) were reviewed.

Abstract
The mathematical analysis for plasma disappearance curve of aflatoxicosed animals, subsequently injected with 45Ca was determined. The analysis showed that the three main compartments of the calcium pool (plasma, bone and the labile calcium pool on the surface of bone and soft tissues) had been affected.Specifically, the fractional rate constant for migration of 45Ca from plasma pool to the labile pool had been diminished to its third value. This led to a corresponding reduction in the calcium content of the bone ash.The probable mechanism by which aflatoxin B r affects calcium dynamics may be interpreted by the inhibitory effect of aflatoxin in the hydroxylation mechanism of vitamin D 3 into an active intermediate. During aflatoxicosis (induction of 15 days) the animals entered a state of calcium deficiency, secondary to intestinal absorption inhibition. This was followed by bone resorption and disturbance of the fractional removal rate constant among different calcium compartments.

A total of 506 isolates of mesophilic, thermophilic and thermotolerant fungi isolated from the poultry feed ingredients included soybean meals, ground maize, cottonseed cake, wheat bran and fish meal, on glucose‐CZAPEK's agar, LITTMAN oxgall agar at 28 °C and yeast starch agar (YPSs) at 45 °C, were screened for their ability to produce hydrolytic protease enzyme on solid media. Most of the fungal isolates were able to produce such enzymes but with variable capabilities. The highest proteolytic activity was exhibited by some isolates of Penicillium chrysogenum, Aspergillus flavus, Thermoascus thermophilus and Rhizopus chizopodifarmis. Of all fungal isolates screened for proteolytic activity, Penicillium chrysogenum and Thermoascus thermophilus produced the highest amounts of proteases. These two isolates were used to study the effect of some environmental and nutritional factors on their proteolytic …

CiNii 論文 - Bradykinin potentiating fraction isolated from venom of Buthus occitanus promotes spermatogenesis in premature mice CiNii 国立情報学研究所 学術情報ナビゲータ[サイニィ ] 日本の論文をさがす 大学図書館の本をさがす 日本の博士論文をさがす 新規登録 ログイン English 検索 すべて 本文あり すべて 本文あり 閉じる タイトル 著者名 著者ID 著者所属 刊行物名 ISSN 巻号 ページ 出版者 参考文献 出版年 年から 年まで 検索 検索 検索 [10/4更新]2022年4月1日からの CiNii ArticlesのCiNii Researchへの統合について Bradykinin potentiating fraction isolated from venom of Buthus occitanus promotes spermatogenesis in premature mice NASSAR AY 被引用 文献: 1件 著者 NASSAR AY 収録刊行物 Rec. Advan. Toxinol. Res. Rec. Advan. Toxinol. Res. 2, 119-135, 1992 被引用文献: 1件中 1-1件を 表示 1 A Scorpion Venom Peptide Fraction Induced Prostaglandin Biosynthesis in Guinea Pig Kidneys : Incorporation of ^<14>C-Linoleic …