Do you have any questions? 
Basic Statistics Course for Postgraduate Students Organized by the Department of Obstetrics and Gynecology
Congratulations from the Faculty of Medicine to Professor Dr. Saad Zaki Mahmoud
Congratulations from the Faculty of Medicine to Professor Dr. Saad Zaki Mahmoud
تهنئة اسرة كلية الطب الدكتور/ ياسر فاروق عبدالرحيم لتعيينه مديراً لمستشفى الاطفال الجامعى
تهنئة اسرة كلية الطب
الدكتور/ ياسر فاروق عبدالرحيم لتعيينه مديراً لمستشفى الاطفال الجامعى
Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry
Congratulations to the Faculty of Medicine family
Professor Dr. / Mona Abdel Hamid El-Baz
On the occasion of her appointment as Head of the Department of Medical Biochemistry
Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry
Congratulations to the Faculty of Medicine family
Professor Dr. / Mona Abdel Hamid El-Baz
On the occasion of her appointment as Head of the Department of Medical Biochemistry
Congratulations to the Faculty of Medicine family Prof. Dr. Hatem Galal Zaki for assuming the position of President-Elect of the International Society of Orthopaedic Surgery SICOT
Congratulations to the Faculty of Medicine family
Prof. Dr. Hatem Galal Zaki for assuming the position of President-Elect of the International Society of Orthopaedic Surgery SICOT
Invitation to discuss the doctoral thesis of Dr. Hadeer Mustafa Hassouna - Assistant Lecturer, Department of Clinical Pathology - Faculty of Medicine - Assiut University
Invitation to discuss the doctoral thesis of Dr. Hadeer Mustafa Hassouna - Assistant Lecturer, Department of Clinical Pathology - Faculty of Medicine - Assiut University
Impact of porous microsponges in minimizing myotoxic side effects of simvastatin
Research Abstract
Simvastatin (SV) is a poorly soluble drug; its oral administration is associated with a significant problem: Myopathy. The present study aims to formulate SV microsponges that have the potential to minimize the myotoxicity accompanying the oral administration of the drug. SV microsponges were prepared by exploiting the emulsion solvent evaporation technique. The % entrapment efficiency (%EE) of the drug approached 82.54 ± 1.27%, the mean particle size of SV microsponges ranged from 53.80 ± 6.35 to 86.03 ± 4.79 µm in diameter, and the % cumulative drug release (%CDR) of SV from microsponges was significantly higher than that from free drug dispersion much more, the specific surface area of the optimized microsponges formulation was found to be 16.6 m2/g revealed the porosity of prepared microsponges. Histological and glycogen histochemical studies in the skeletal muscles of male albino rats revealed that microsponges were safer than free SV in minimizing myotoxicity. These findings were proven by Gene expression of Mitochondrial fusion and fission (Mfn1) & (Fis1) and (Peroxisome proliferator-activated receptor gamma co-activator 1α) PGC-1α. Finally, our study ascertained that SV microsponges significantly decreased the myotoxicity of SV.
Research Department
Research Journal
scientific reports
Research Member
Research Year
2023
Comparative study between surgical wound catheter, femoral nerve block, and adductor canal block for postoperative analgesia after knee arthroplasty: A double blind randomized …
Research Date
Research Department
Research Journal
Saudi Journal of Anaesthesia
Research Member
Research Year
2023
Effect of Magnesium Sulfate on the Total Anesthetic and Analgesic Requirements in Neurosurgery
Research Date
Research Department
Research Journal
Journal of Spine Practice (JSP)
Research Member
Research Year
2021