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Abstract: Background: There is an interesting growing evidence for a relation between bronchiolitis and vitamin D. This suggests a possible benefit from Vitamin D therapy to children with bronchiolitis. Methods: We performed a double-blind, randomized clinical trial on 89 infants with bronchiolitis. Patients were randomized to receive vitamin D or placebo. Results: The intervention group, which received vitamin D therapy, had significant improvement in 3 parameters: The mean time taken for resolution of the disease, the mean time taken for the improvement of oral feeding and the duration of hospitalization. All these outcomes in the intervention group (vitamin D) were significantly better than the control (placebo) group with p 0.001, 0.05 and 0.01 respectively. Our study supported the efficacy of vitamin D therapy in bronchiolitis. Conclusion: This double-blinded, randomized placebo controlled trial of vitamin D supplementation 100 IU/kg daily in Egyptian children with bronchiolitis found a clinically and statistically significant reduction in hospitalization with rapid recovery of the disease. Our study suggested that short term supplementation with Vitamin D given daily during the course of illness, starting from day one, may help in resolution of bronchiolitis.

Abstract: Background: There is an interesting growing evidence for a relation between bronchiolitis and vitamin D. This suggests a possible benefit from Vitamin D therapy to children with bronchiolitis. Methods: We performed a double-blind, randomized clinical trial on 89 infants with bronchiolitis. Patients were randomized to receive vitamin D or placebo. Results: The intervention group, which received vitamin D therapy, had significant improvement in 3 parameters: The mean time taken for resolution of the disease, the mean time taken for the improvement of oral feeding and the duration of hospitalization. All these outcomes in the intervention group (vitamin D) were significantly better than the control (placebo) group with p 0.001, 0.05 and 0.01 respectively. Our study supported the efficacy of vitamin D therapy in bronchiolitis. Conclusion: This double-blinded, randomized placebo controlled trial of vitamin D supplementation 100 IU/kg daily in Egyptian children with bronchiolitis found a clinically and statistically significant reduction in hospitalization with rapid recovery of the disease. Our study suggested that short term supplementation with Vitamin D given daily during the course of illness, starting from day one, may help in resolution of bronchiolitis.

Abstract: Background: There is an interesting growing evidence for a relation between bronchiolitis and vitamin D. This suggests a possible benefit from Vitamin D therapy to children with bronchiolitis. Methods: We performed a double-blind, randomized clinical trial on 89 infants with bronchiolitis. Patients were randomized to receive vitamin D or placebo. Results: The intervention group, which received vitamin D therapy, had significant improvement in 3 parameters: The mean time taken for resolution of the disease, the mean time taken for the improvement of oral feeding and the duration of hospitalization. All these outcomes in the intervention group (vitamin D) were significantly better than the control (placebo) group with p 0.001, 0.05 and 0.01 respectively. Our study supported the efficacy of vitamin D therapy in bronchiolitis. Conclusion: This double-blinded, randomized placebo controlled trial of vitamin D supplementation 100 IU/kg daily in Egyptian children with bronchiolitis found a clinically and statistically significant reduction in hospitalization with rapid recovery of the disease. Our study suggested that short term supplementation with Vitamin D given daily during the course of illness, starting from day one, may help in resolution of bronchiolitis.

Abstract: Background: There is an interesting growing evidence for a relation between bronchiolitis and vitamin D. This suggests a possible benefit from Vitamin D therapy to children with bronchiolitis. Methods: We performed a double-blind, randomized clinical trial on 89 infants with bronchiolitis. Patients were randomized to receive vitamin D or placebo. Results: The intervention group, which received vitamin D therapy, had significant improvement in 3 parameters: The mean time taken for resolution of the disease, the mean time taken for the improvement of oral feeding and the duration of hospitalization. All these outcomes in the intervention group (vitamin D) were significantly better than the control (placebo) group with p 0.001, 0.05 and 0.01 respectively. Our study supported the efficacy of vitamin D therapy in bronchiolitis. Conclusion: This double-blinded, randomized placebo controlled trial of vitamin D supplementation 100 IU/kg daily in Egyptian children with bronchiolitis found a clinically and statistically significant reduction in hospitalization with rapid recovery of the disease. Our study suggested that short term supplementation with Vitamin D given daily during the course of illness, starting from day one, may help in resolution of bronchiolitis.

Abstract: Background: There is an interesting growing evidence for a relation between bronchiolitis and vitamin D. This suggests a possible benefit from Vitamin D therapy to children with bronchiolitis. Methods: We performed a double-blind, randomized clinical trial on 89 infants with bronchiolitis. Patients were randomized to receive vitamin D or placebo. Results: The intervention group, which received vitamin D therapy, had significant improvement in 3 parameters: The mean time taken for resolution of the disease, the mean time taken for the improvement of oral feeding and the duration of hospitalization. All these outcomes in the intervention group (vitamin D) were significantly better than the control (placebo) group with p 0.001, 0.05 and 0.01 respectively. Our study supported the efficacy of vitamin D therapy in bronchiolitis. Conclusion: This double-blinded, randomized placebo controlled trial of vitamin D supplementation 100 IU/kg daily in Egyptian children with bronchiolitis found a clinically and statistically significant reduction in hospitalization with rapid recovery of the disease. Our study suggested that short term supplementation with Vitamin D given daily during the course of illness, starting from day one, may help in resolution of bronchiolitis.

Abstract The aim of this study is to detect the risk factors associated with otitis media with effusion (OME) among children with age ranged from 6 months to 2 years. Materials and Methods: it is a crosssectional study 500 children were selected from Assiut University Hospital clinics through multistaged randomized sampling. Parents of these children were interviewed with a structured questionnaire. Clinical examination, including otoscopic examination and tympanometry was performed for each child. Results: There was no statistical significant relationship between OME and gender, age, mother job. There is statistical significant relationship between OME and breast feeding, using pacifier, mother education, sibling of children and exposure to passive smoking. Conclusion: There are multiple risk factors associated with OME in children between 6 months to 2 years of age.

Abstract: Neonatal period is the most hazardous period of life because of various problems/ diseases which a neonate faces. There is great over lap between the risks associated with morbidity and mortality in the perinatal and neonatal periods. The present study aimed to identify the profile and risk factors for neonatal mortality among neonates admitted to neonatal intensive care unit (NICU) in pediatric Assiut University Hospital (AUH). A prospective study was conducted in NICU of pediatric AUH. Study population included all neonates admitted to NICU over a period of one year. The data collected included detailed antenatal and natal histories, details of clinical examination, primary diagnosis, progress during the hospital stay and outcome. The outcome measure was inhospital death. Survival was defined as the discharge of a live infant from the NICU. Differences between deceased and survived neonates were estimated by the chi-square test and t-test. The association between risk factors and neonatal mortality were estimated by relative risk. The significance level used was p-value of less than 0.05. A total of 990 neonates were included in the study, of which 582 neonates (58.8%) died during their hospital stay. The mortality rate decreased with the increase in birth weight, as well as gestational age. Respiratory distress was the commonest primary diagnosis (94.5%) among all admitted neonates, followed by very low birth weight (VLBW) (36.7%), congenital malformations (8.2%), and infections (4.4%). Significant risk factors (P0.05) associated with neonatal mortality were: vaginal delivery, multiple births, low Apgar score at 5 minutes, neonatal respiratory distress, prematurity, and low birth weight (LBW). It is concluded that majority of the causes of neonatal mortality are preventable. Surveillance programs for neonatal death should include preventive actions and interventions for the perinatal period. Focused initiatives for quality improvement may also be necessary. [Eman M. Mohamed, Asmaa M. A. Soliman, Osama M. El-Asheer. Predictors of mortality among neonates admitted to neonatal intensive care unit in pediatric Assiut University Hospital, Egypt.

Abstract: Neonatal period is the most hazardous period of life because of various problems/ diseases which a neonate faces. There is great over lap between the risks associated with morbidity and mortality in the perinatal and neonatal periods. The present study aimed to identify the profile and risk factors for neonatal mortality among neonates admitted to neonatal intensive care unit (NICU) in pediatric Assiut University Hospital (AUH). A prospective study was conducted in NICU of pediatric AUH. Study population included all neonates admitted to NICU over a period of one year. The data collected included detailed antenatal and natal histories, details of clinical examination, primary diagnosis, progress during the hospital stay and outcome. The outcome measure was inhospital death. Survival was defined as the discharge of a live infant from the NICU. Differences between deceased and survived neonates were estimated by the chi-square test and t-test. The association between risk factors and neonatal mortality were estimated by relative risk. The significance level used was p-value of less than 0.05. A total of 990 neonates were included in the study, of which 582 neonates (58.8%) died during their hospital stay. The mortality rate decreased with the increase in birth weight, as well as gestational age. Respiratory distress was the commonest primary diagnosis (94.5%) among all admitted neonates, followed by very low birth weight (VLBW) (36.7%), congenital malformations (8.2%), and infections (4.4%). Significant risk factors (P0.05) associated with neonatal mortality were: vaginal delivery, multiple births, low Apgar score at 5 minutes, neonatal respiratory distress, prematurity, and low birth weight (LBW). It is concluded that majority of the causes of neonatal mortality are preventable. Surveillance programs for neonatal death should include preventive actions and interventions for the perinatal period. Focused initiatives for quality improvement may also be necessary. [Eman M. Mohamed, Asmaa M. A. Soliman, Osama M. El-Asheer. Predictors of mortality among neonates admitted to neonatal intensive care unit in pediatric Assiut University Hospital, Egypt.

Abstract: Neonatal period is the most hazardous period of life because of various problems/ diseases which a neonate faces. There is great over lap between the risks associated with morbidity and mortality in the perinatal and neonatal periods. The present study aimed to identify the profile and risk factors for neonatal mortality among neonates admitted to neonatal intensive care unit (NICU) in pediatric Assiut University Hospital (AUH). A prospective study was conducted in NICU of pediatric AUH. Study population included all neonates admitted to NICU over a period of one year. The data collected included detailed antenatal and natal histories, details of clinical examination, primary diagnosis, progress during the hospital stay and outcome. The outcome measure was inhospital death. Survival was defined as the discharge of a live infant from the NICU. Differences between deceased and survived neonates were estimated by the chi-square test and t-test. The association between risk factors and neonatal mortality were estimated by relative risk. The significance level used was p-value of less than 0.05. A total of 990 neonates were included in the study, of which 582 neonates (58.8%) died during their hospital stay. The mortality rate decreased with the increase in birth weight, as well as gestational age. Respiratory distress was the commonest primary diagnosis (94.5%) among all admitted neonates, followed by very low birth weight (VLBW) (36.7%), congenital malformations (8.2%), and infections (4.4%). Significant risk factors (P0.05) associated with neonatal mortality were: vaginal delivery, multiple births, low Apgar score at 5 minutes, neonatal respiratory distress, prematurity, and low birth weight (LBW). It is concluded that majority of the causes of neonatal mortality are preventable. Surveillance programs for neonatal death should include preventive actions and interventions for the perinatal period. Focused initiatives for quality improvement may also be necessary. [Eman M. Mohamed, Asmaa M. A. Soliman, Osama M. El-Asheer. Predictors of mortality among neonates admitted to neonatal intensive care unit in pediatric Assiut University Hospital, Egypt.