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Effect of Pediatric Nasal Surgical Procedures done in Conjunction with Endoscopic Transnasal Adenoidectomy on the Postoperative Outcome

Research Abstract
Objective: to evaluate whether nasal surgical procedures done in conjunction with adenoidectomy in children affect the outcome of the procedure. Patients and methods: Patients were classified into 2 groups.Group A included patients undergone adenoidectomy alone, and group B which included patients undergone adenoidectomy and surgical nasal procedure(s). Patients were followed up 1, 2, 4 weeks, 6 months and 1 year postoperatively for presence of edema, discharge, crusts, adhesions and overall nasal patency. Results: No statistically significant differences were observed in the presence of postoperative edema, discharge, crusts, adhesions and nasal patency between the 2 groups. Conclusion: Nasal surgical procedures can be done safely effectively with endoscopic adenoidectomy in children.
Research Authors
Osman, M.M. & Abd Elrahim, A.G.
Research Journal
Egyptian Journal of Neck Surgery and Otolaryngology
Research Pages
41-48
Research Publisher
NULL
Research Rank
2
Research Vol
Vol. 2, No. 2
Research Website
NULL
Research Year
2015

Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?

Research Abstract
Objective: Detect whether bone erosion or destruction alters the ADC value while discriminating benign from malignant sinonasal masses. Patients and methods: Twenty five patients were investigated and operated upon in this study. Preoperative CT scans and diffusion weighted MRI imaging were done within 48 hours prior to surgery. Surgical procedures were done in the form of complete resection or biopsy taking. The ADC values were calculated for sinonasal lesions associated with bone erosion or destruction detected on CT scanning. Results: Histopathological diagnosis revealed benign masses in 44% and malignant tumors in 56% of biopsies. No significant differences between mean ADC values of the first and second ROI in both benign (P value =0.365) and malignant masses (P value =0. 07). Statistical significant difference was found between the ADCL values of benign and malignant sinonasal masses. (P value =0.044). Conclusions: Bone erosion or destruction does not alter the ADC value in differentiating between benign and malignant masses. ADC value does not change with bone erosion or destruction.
Research Authors
Osman, M.M., Soliman, R. K., and Imam, H. M. K
Research Journal
Egyptian Journal of Neck Surgery and Otolaryngology
Research Pages
33-40
Research Publisher
NULL
Research Rank
2
Research Vol
Vol. 2, No. 2
Research Website
NULL
Research Year
2015

Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?

Research Abstract
Objective: Detect whether bone erosion or destruction alters the ADC value while discriminating benign from malignant sinonasal masses. Patients and methods: Twenty five patients were investigated and operated upon in this study. Preoperative CT scans and diffusion weighted MRI imaging were done within 48 hours prior to surgery. Surgical procedures were done in the form of complete resection or biopsy taking. The ADC values were calculated for sinonasal lesions associated with bone erosion or destruction detected on CT scanning. Results: Histopathological diagnosis revealed benign masses in 44% and malignant tumors in 56% of biopsies. No significant differences between mean ADC values of the first and second ROI in both benign (P value =0.365) and malignant masses (P value =0. 07). Statistical significant difference was found between the ADCL values of benign and malignant sinonasal masses. (P value =0.044). Conclusions: Bone erosion or destruction does not alter the ADC value in differentiating between benign and malignant masses. ADC value does not change with bone erosion or destruction.
Research Authors
Osman, M.M., Soliman, R. K., and Imam, H. M. K
Research Journal
Egyptian Journal of Neck Surgery and Otolaryngology
Research Pages
33-40
Research Publisher
NULL
Research Rank
2
Research Vol
Vol. 2, No. 2
Research Website
NULL
Research Year
2015

Diffusion-weighted Magnetic Resonance Imaging of Sinonasal Masses: Does Bone Erosion or Destruction Alter the Apparent Diffusion Coefficient Value in Differentiating Benign from Malignant Masses?

Research Abstract
Objective: Detect whether bone erosion or destruction alters the ADC value while discriminating benign from malignant sinonasal masses. Patients and methods: Twenty five patients were investigated and operated upon in this study. Preoperative CT scans and diffusion weighted MRI imaging were done within 48 hours prior to surgery. Surgical procedures were done in the form of complete resection or biopsy taking. The ADC values were calculated for sinonasal lesions associated with bone erosion or destruction detected on CT scanning. Results: Histopathological diagnosis revealed benign masses in 44% and malignant tumors in 56% of biopsies. No significant differences between mean ADC values of the first and second ROI in both benign (P value =0.365) and malignant masses (P value =0. 07). Statistical significant difference was found between the ADCL values of benign and malignant sinonasal masses. (P value =0.044). Conclusions: Bone erosion or destruction does not alter the ADC value in differentiating between benign and malignant masses. ADC value does not change with bone erosion or destruction.
Research Authors
Osman, M.M., Soliman, R. K., and Imam, H. M. K
Research Journal
Egyptian Journal of Neck Surgery and Otolaryngology
Research Pages
33-40
Research Publisher
NULL
Research Rank
2
Research Vol
Vol. 2, No. 2
Research Website
NULL
Research Year
2015

Impact of Resection of the Head of Middle Turbinate
in Endoscopic Sinus Surgery

Research Abstract
Objective: The aim of our study was to evaluate the effects of middle turbinate head resection (MTR) on the outcome of endoscopic sinus surgery. Patients and methods: Patients with bilateral nasal polyps were bilaterally operated upon. In one side, the polyps were removed with preservation of the head of middle turbinate. In the other side, polyps were removed with resection of the head of middle turbinate. Patients were followed up at 1, 2, 4 weeks, 6 months, 1 and 2 years postoperatively for the presence of crusts, adhesions, polyp recurrence, smell affection, frontal sinus drainage pathway obstruction and overall nose patency. The duration of surgery in both sides was also compared. Results: No statistically significant differences were observed in the presence of crusts, adhesions, polyp recurrence, smell affection, frontal sinus drainage pathway obstruction and overall nasal patency between the 2 operated sides. The operative time was significantly shorter in the group with (MTR). Conclusion: Resection of the head of middle turbinate carries no adverse effects and can be done safely in endoscopic sinus surgery.
Research Authors
Hamza El-Shafaai A Ahmed
Mohamed M Osman
Research Journal
Pan Arab Journal of Rhinology
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2016

Impact of Resection of the Head of Middle Turbinate
in Endoscopic Sinus Surgery

Research Abstract
Objective: The aim of our study was to evaluate the effects of middle turbinate head resection (MTR) on the outcome of endoscopic sinus surgery. Patients and methods: Patients with bilateral nasal polyps were bilaterally operated upon. In one side, the polyps were removed with preservation of the head of middle turbinate. In the other side, polyps were removed with resection of the head of middle turbinate. Patients were followed up at 1, 2, 4 weeks, 6 months, 1 and 2 years postoperatively for the presence of crusts, adhesions, polyp recurrence, smell affection, frontal sinus drainage pathway obstruction and overall nose patency. The duration of surgery in both sides was also compared. Results: No statistically significant differences were observed in the presence of crusts, adhesions, polyp recurrence, smell affection, frontal sinus drainage pathway obstruction and overall nasal patency between the 2 operated sides. The operative time was significantly shorter in the group with (MTR). Conclusion: Resection of the head of middle turbinate carries no adverse effects and can be done safely in endoscopic sinus surgery.
Research Authors
Hamza El-Shafaai A Ahmed
Mohamed M Osman
Research Journal
Pan Arab Journal of Rhinology
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2016

Prevalence of Bell’s palsy in Qena Governorate, Egypt

Research Abstract
Background and purpose: There have been few studies to estimate the prevalence of Bell’s palsy (BP) in Arab countries. A community-based study was conducted to estimate the prevalence, incidence rates, precipitating factors, and outcome of BP in Qena Governorate, Egypt. Subjects and methods: A door-to-door survey was carried out, with random sampling of 10 districts, involving 9303 inhabitants, 51.1% males and 48.9% females. Seventeen subjects were positive in screening questionnaire and referred to Qena University hospital and were subjected to a full clinical examination, House Brackmann’s Facial grading system. Results: In a total population of 9303 individuals, 15 cases were confirmed as having BP giving a prevalence rate (PR) 161/105 for all ages 95%CI (80–243). It was slightly but not significantly higher among women and the rural community. The incidence rate of BP was 107/105. The highest age-specific rate was 40–49 years age. The most frequent precipitating factors for an episode of BP were exposure to air draft in 40%, physical stress (13.3%), and upper respiratory tract infection (13.3%). Moreover, 46.7% had predisposing risk factors, DM and hypertension in 33.3%. Sixty percent of cases had complication and poor outcome. Conclusion: The overall prevalence and incidence rates of BP in Qena governorate were high. This could be related to the variation in day and night temperature in our community and the susceptibility to air draft exposure during the night. The high frequency of poor outcome among studied cases suggests that better local guidelines should be implemented to recognize and treat BP.
Research Authors
Eman M. Khedra*, Gharib Fawib, Mohammed Abd Allah Abbasc, Noha Abo El-Fetoha, Ahmed F. Zakic & Ayman Gameac
Research Journal
Neurological Research
Research Pages
NULL
Research Publisher
Taylor & Francis Group
Research Rank
1
Research Vol
NULL
Research Website
DOI:10.1080/01616412.2016.1190121
Research Year
2016

Prevalence of Bell’s palsy in Qena Governorate, Egypt

Research Abstract
Background and purpose: There have been few studies to estimate the prevalence of Bell’s palsy (BP) in Arab countries. A community-based study was conducted to estimate the prevalence, incidence rates, precipitating factors, and outcome of BP in Qena Governorate, Egypt. Subjects and methods: A door-to-door survey was carried out, with random sampling of 10 districts, involving 9303 inhabitants, 51.1% males and 48.9% females. Seventeen subjects were positive in screening questionnaire and referred to Qena University hospital and were subjected to a full clinical examination, House Brackmann’s Facial grading system. Results: In a total population of 9303 individuals, 15 cases were confirmed as having BP giving a prevalence rate (PR) 161/105 for all ages 95%CI (80–243). It was slightly but not significantly higher among women and the rural community. The incidence rate of BP was 107/105. The highest age-specific rate was 40–49 years age. The most frequent precipitating factors for an episode of BP were exposure to air draft in 40%, physical stress (13.3%), and upper respiratory tract infection (13.3%). Moreover, 46.7% had predisposing risk factors, DM and hypertension in 33.3%. Sixty percent of cases had complication and poor outcome. Conclusion: The overall prevalence and incidence rates of BP in Qena governorate were high. This could be related to the variation in day and night temperature in our community and the susceptibility to air draft exposure during the night. The high frequency of poor outcome among studied cases suggests that better local guidelines should be implemented to recognize and treat BP.
Research Authors
Eman M. Khedra*, Gharib Fawib, Mohammed Abd Allah Abbasc, Noha Abo El-Fetoha, Ahmed F. Zakic & Ayman Gameac
Research Journal
Neurological Research
Research Member
Research Pages
NULL
Research Publisher
Taylor & Francis Group
Research Rank
1
Research Vol
NULL
Research Website
DOI:10.1080/01616412.2016.1190121
Research Year
2016

Dopamine levels after repetitive transcranial magnetic stimulation of motor cortex in patients with Parkinson's disease: preliminary results.

Research Abstract
Abstract BACKGROUND: Repeated session of repetitive transcranial magnetic stimulation (rTMS) over motor cortex have been reported to produce significant improvement of motor performance in patients with parkinson's disease (PD). In addition, it is known that a single session of rTMS over motor cortex transiently increases DA in striatum. Here, we test whether repeated sessions of rTMS increase serum dopamine in PD patients and whether this correlates with changes in clinical rating scales. MATERIAL AND METHODS: Twenty untreated PD patients with moderate to severe symptoms (Hoehn & Yahr state III-V 1967) were assessed on the Unified Parkinson's Disease Rating Scale (UPDRS), and with an enzyme immunoassay for quantitative determination of plasma dopamine before and after six daily sessions of 25 Hz rTMS with 3,000 stimuli over the right and left hand and leg motor cortex. RESULTS: There was significant improvement in UPDRS compared with the baseline. Serum dopamine level also was significantly elevated over the same interval. There was a significant correlation between UPDRS and serum dopamine level before and after treatment. CONCLUSION: Improved motor performance in PD after repeated session of rTMS may be related to an elevation of serum dopamine concentration.
Research Authors
Khedr EM1, Rothwell JC, Shawky OA, Ahmed MA, Foly N, Hamdy A.
Research Journal
Mov Disord. 2007 May 15;22(7):1046-50.
Research Member
Research Pages
1046-50
Research Publisher
Elsevier
Research Rank
1
Research Vol
22(7)
Research Website
PubMed - indexed for MEDLINE
Research Year
2007

Dopamine levels after repetitive transcranial magnetic stimulation of motor cortex in patients with Parkinson's disease: preliminary results.

Research Abstract
Abstract BACKGROUND: Repeated session of repetitive transcranial magnetic stimulation (rTMS) over motor cortex have been reported to produce significant improvement of motor performance in patients with parkinson's disease (PD). In addition, it is known that a single session of rTMS over motor cortex transiently increases DA in striatum. Here, we test whether repeated sessions of rTMS increase serum dopamine in PD patients and whether this correlates with changes in clinical rating scales. MATERIAL AND METHODS: Twenty untreated PD patients with moderate to severe symptoms (Hoehn & Yahr state III-V 1967) were assessed on the Unified Parkinson's Disease Rating Scale (UPDRS), and with an enzyme immunoassay for quantitative determination of plasma dopamine before and after six daily sessions of 25 Hz rTMS with 3,000 stimuli over the right and left hand and leg motor cortex. RESULTS: There was significant improvement in UPDRS compared with the baseline. Serum dopamine level also was significantly elevated over the same interval. There was a significant correlation between UPDRS and serum dopamine level before and after treatment. CONCLUSION: Improved motor performance in PD after repeated session of rTMS may be related to an elevation of serum dopamine concentration.
Research Authors
Khedr EM1, Rothwell JC, Shawky OA, Ahmed MA, Foly N, Hamdy A.
Research Journal
Mov Disord. 2007 May 15;22(7):1046-50.
Research Member
Research Pages
1046-50
Research Publisher
Elsevier
Research Rank
1
Research Vol
22(7)
Research Website
PubMed - indexed for MEDLINE
Research Year
2007
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