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A Full Day Tour to El-Moez St., Citadel of Saladin, and Dream Park

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The social committee of the public department of Youth Welfare office is organizing a full day tour to El-Moez St., the Citadel of Saladin, and Dream Park for 250 L.E. on Saturday 19-11-2022. The deadline for registration 17-11-2022. For registration, kindly visit the stadium.

OXALIPLATIN ANTICANCER DRUG ACTION IN EXPERIMENTALLY INDUCED ORAL CARCINOGENESIS BY ASSESSED DNA FLOW CYTOMETRY

Research Abstract

Introduction: Oral squamous cell carcinoma is one of the most widespread cancer which totalizes more than 90% of oral malignancies. Therefore, the conception of detaining or preventing the malignant transformation remains a viable target for future. Oxaliplatin is a third-generation platinum based chemotherapy cure that has value in the treatment against several forms of neoplasms. It forms intrastrand links between two adjoining DNA bases, hence disrupting its replication and transcription.

Aim of the study: The current work was carried out to report the oxaliplatin drug as a chemotherapeutic agent during DMBA-induced carcinoma in hamster buccal pouch, utilizing histopathology and flow cytometry analysis.

Material and methods: A total of 60 Syrian hamsters distributed as 2 animals examined for the normal pouch mucosa and 58 hamsters divided into; 6 experiments for Group I, their pouches were painted only with mineral oil. The remaining 52 animals for Group II, treated by DMBA mixed in a mineral oil. After 6 weeks, the hamsters separated into 2 subgroups; Group IIA, were persisted operated in DMBA. Group IIB, were employed to DMBA and injected with oxaliplatin.

Results: Oxaliplatin revealed effectiveness and tolerance in turn down the DMBA carcinogenesis procedure. Additionally, the chemotherapeutic results of oxaliplatin detected a significant reduction relation to the DNA aneuploidy and the S-phase fraction throughout the tumorigenic activity.

Conclusion: Oxaliplatin provided a proper strategy as a chemotherapeutic curing for control oral carcinogenesis process with a notable reduction of cancer incidence through reducing the nuclear proliferation activity and induction of cellular apoptosis.

Research Authors
Ahmed M. Hussein, Mohamed Badawy, Ibraheem Mahmoud Mwafey, Omar H. Soliman
Research Date
Research Department
Research File
Research Journal
Egyptian Dental Journal
Research Pages
167-179
Research Publisher
Egyptian Dental Association
Research Vol
69
Research Website
https://edj.journals.ekb.eg/article_280325.html
Research Year
2023

Opening a New Seminar Hall in Faculty of Dentistry

The Faculty of Dentistry opened a new seminar hall on Wednesday 9-11-2022. The first activity held in this hall was the scientific day of Endodontics Department entitled, “Difficult Cases in Endodontics Prognosis and Prophylaxis of Complications” which was attended by head of Assiut Dental Syndicate and many staff members and dentists.

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Technical Support of Quality Assurance and Accreditation Visit to Faculty of Dentistry

The technical support of Quality Assurance and Accreditation visited the Faculty of Dentistry from 25 to 27 October to check up lecture halls, laboratories, and the dental hospital, and to hold a meeting with the staff, administrators, and students to provide the staff with their observations and reviews before the new visit from Quality Assurance and Accreditation Unit.

The technical support team includes:

  1. Prof/ Ibrahim Muhammad Ismail (Director of Quality Assurance Unit in Assiut University and Head of the team).
  2. Prof/ Muhammad Abd El-Baset (Faculty of Engineering - member)
  3. Prof/Salwa Abd El-Rahman Megahed (Faculty of Engineering -Member)
  4. Prof/ Hassan Refat Hassan (Head of Quality Assurance Unit – Faculty of Pharmacy)

The Quality Assurance Team of the Faculty of Dentistry includes:

  1. Prof/ Mohamed Abdul Maged Katamish (Dean of the Faculty of Dentistry)
  2. Prof/ Naglaa El-Meligy the Vice Dean for Education and Student Affairs
  3. Prof Heba Rashed Vice Dean for Community Services and Environmental Development)
  4. Dr./ Alzahraa Muhammad Ibrahim (Head of the Quality Assurance Unit in the Faculty of Dentistry)
  5. Dr./ Rana Muhammad Hashim (Vice-president Quality Assurance Unit
  6. Mr./ Montaser Hussein Ahmad (managing Director of the Unit)
  7. Coordinators of the Quality Assurance Unit.

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Competition for Best Quran Reciter and Best Event and Symposium Presenter

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The cultural committee of the youth welfare office will hold a competition to choose the best Quran reciter and the best event and symposium presenter on Wednesday 16-11-2022. The deadline for registration is Tuesday 15-11-2022.

For registration, kindly visit the youth welfare office.

Faculty of Dentistry Honors its Top Ten Students during its 5th Graduation Day

The Faculty of Dentistry Honored its top ten students during its 5th graduation day that was held on Sunday 30-10-2022.The Faculty of Dentistry Honored its top ten students during its 5th graduation day that was held on Sunday 30-10-2022.

1- George Nasser Farid

2- Abd El-Rahman Ahmad Mahrous

3- Wafaa Taher Muhammad

4- Raghada Sala-El-Din

5- Rana Alaa El-Din

6- Nada Muhammad Abd El-Khalik

7- Nada Yasse Abo- Bakr

8- Rehab Atef Abd El-Tawwab

9- Ahmad Badr Ghareeb

10- Zakaria Khallaf  Abd El-Hakim

 

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