tRaw buffalo milk samples from the agroindustrial zone in upper Egypt were ana-lyzed for the presence of organochlorine and organophosphorus pesticides using gaschromatography–mass spectroscopy. Five organochlorine pesticides namely, alachlor, dield-rin, hexachlorobenzene, lindane and methoxychlor and three organophosphorus pesticideschlorpyrifos, malathion, and parathion-methyl were detected in the milk samples. In 44%of the samples, the concentrations of lindane and malathion residues exceeded tolerancelevels set by the European Commission (EC) in 2008. In addition, the concentrations of chlor-pyrifos, methoxychlor, and hexachlorobenzene residues exceeded the 2008 EC maximumresidual limits (MRLs) by 33, 66, and 88% of the examined samples, respectively. However,the levels of alachlor, dieldrin, and parathion-methyl residues were below EC MRLs. Theresults of this study confirm the risks of pesticide residues exposure that threaten con-sumer health in Egypt. Thus, we recommend that pesticide residue monitoring programsbe instituted in all the developing countries