A new series of 2-aryl(alkyl)oxazoloquinolines (IV) were prepared by the reaction of 7-amino-8-hydroxyquinoline with aromatic (or aliphatic) aldehydes in the presence of piperidine as a catalyst. Interaction of 2-methyloxazolo[4,5-h]quinoIine with aromatic aldehydes in the presence of piperidine as a catalyst gave 2-stilbyloxazolo [4,5-h]quinolines. The structural configuration of the prepared compounds was determined by elemental and spectral analysis.