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Synthesis of Morphlinotetrahydrothieno[2,3-c]isoquinolines

Research Abstract

1-Morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (2) was synthesized from 3-amino-
1-thioxo-5,6,7,8-tetrahydro-1H-isothiochromene-4-carbonitrile (1) and used as starting material to synthesize many thienotetrahydroisoquinolines (4),which in turn were used in the synthesis of many pyrimidothienotetrahydroisoquinolines.

Research Authors
Adel M. Kamal El-Dean, Shaban M. Radwan and Remon M. Zaki
Research Department
Research Journal
Journal of the Chinese Chemical Society
Research Pages
1290-1299
Research Publisher
Chinese Chemical Society
Research Rank
1
Research Vol
55
Research Year
2008