In this study, gamma-rays, neutrons, electrons, and charge particles interaction properties with {75[70TeO₂ - 30PbO] [(25-x) ZnO- xLi₂O]} where x = 0, 5, 10, 15, and 25 mol% glass systems were investigated. Tellurite glass composites were fabricated using melt-quenching method with densities varied from 6.0909 to 5.7834 g/cm³. The gamma attenuation capability was investigated experimentally using ¹³⁷Cs and ⁶⁰Co sources with NaI(Tl). The gamma shielding parameters were theoretically evaluated across a wide range of energy (0.015 – 15 MeV) with Phy-X/PSD and Py-MLBUF software. Fast neutron/macroscopic removal cross-section FNRCS/MRCS values for fast neutrons were calculated with the software Phy-X/PSD, MRCS, and NGcal software. The range (R) values of selected ions were estimated using the SRIM Monte Carlo code over a wide range (0.01 – 20 MeV). Additionally, continuous slowing …