This study investigates radon concentration and radon exhalation rates in granite rock samples from the Eastern Desert of Egypt, utilizing the Alpha GUARD measurement system. We assessed radon levels in terms of both area (Bq/m²) and mass (Bq/kg), providing a comprehensive analysis of radon emissions from these geological materials. Additionally, we calculated the annual effective doses associated with radon exposure, highlighting the potential health risks for populations in proximity to granite formations. Our findings contribute to a better understanding of radon behavior in granite rocks and underscore the importance of continuous monitoring, especially in radon-prone regions. The results of the study have revealed that the values obtained for the studied samples are higher than the internationally accepted recommended values. Finally, it can be concluded, from the obtained results that causes high risk to humans and cannot used as a safe source in manufacturing the building materials.