Background: Performance indicators used today to determine to what extent nurses render care using quality of care standards. Pin site infection remains a problematic issue face health care providers, so this study aims to explore relation between quality of preventive nursing care provided and incidence of pin site infection. Research hypothesis: incidence of pin site infection among patients who received preventive nursing care would be lesser than those who had exposed to routine hospital care. Research design: A Quazi experimental design was utilized to conduct study. Setting: Study was conducted at Assiut University Hospital. Sample: Sixty patients admitted in trauma department at Assiut University Hospital. Tools: (I): Patient assessment sheet, (II) Infection Staging Tool based on criteria (Checketts et al., 1993): Results: Only two cases Grade I (6.7%) appeared in study group while ten cases (33.3%) grade I, II, III (6.7%, 20.0%, and 6.7 %) respectively appeared in control group. Conclusion: We found that few incidence of pin site infection is associated with quality of the preventive nursing care provided. Recommendation: pin site infection should be used as an indicator for quality of nursing care and as a comparison or benchmarking over time between hospitals. Conducting collaborative workshops between nursing and medical management for health care providers to stress the importance of preventive nursing care as general and for preventing pin site infections as special, and its impact on patients and organization as a whole.