This study was to investigate the obstacles to conducting as well as applying nursing research in Al- Jouf University. It conducted on five main areas at Al-Jouf University which are Faculty of Applied Medical Sciences male and female sections, Faculty of Health Sciences male and female sections at Sakaka city and Faculty of Health Sciences at Al- Qurrayat. All nursing staff in the university was included in this study. A structured questionnaire sheet was developed by the researcher. Results revealed a number of obstacles to conducting nursing research as limited time ( 24% & 52% strongly agree and agree respectively, P ≤ 0.02 and reduced numbers of demonstrators or clinical instructor (56% & 24% strongly agree and agree, respectively, P ≤ 0.003. Administrative constrains as lack of time, money, and clinical equipments, inability of nurses' to deduce clinical research problems represented the most important obstacles to applying results of nursing research in Al- Jouf University. The study concluded that there are a number of obstacles to conducting nursing research at Al – Jouf University among which of statistically significant are: limited time, reduced number of demonstrators or clinical instructors, lack of a library for postgraduate, lack of centers for certain diseases, and absence of postgraduate affairs besides other obstacles to conducting nursing research at Al- Jouf University. Moreover, the study concluded that the most important obstacles to applying results of nursing research are administrative constrains as lack of time, money and clinical equipments and inability of nurses to deduce clinical research problems. The study recommended the necessity of postgraduate library, training of nursing staff on using digital library and educational programs for the public to use local health resources at Sakaka.