Aim

To investigate the pregnancy rate in women with normal uterine cavity and those with previously corrected uterinecavitary lesions, assessed by hysteroscopy in ICSI cycles.

Study Design

A prospective cohort study.

Materials and Methods

The study included women undergoing ICSI cycles. Patients were allocated into two groups,patients with normal uterine cavity (group 1, n=122) and patients with previously corrected uterine cavitary lesions (group < br />2, n=122). Office hysteroscopy was performed post-menstrual. The main outcome measure was clinical pregnancy rate.Secondary outcomes were the implantation rate and the take home baby rate.

Results

In both groups the mean±SD of the total amount of gonadotrophins used, duration of stimulation, peak estradiollevel, endometrial thickness and number of mature follicles, the implantation rate there was not statistically significantdifferent in both groups (2.22 ± 0.84 vs. 2.46 ± 0.95, p=0.419). Also, the pregnancy rate showed no statistically significantdifference between both groups (33.6% vs. 23.8%, p=0.089).

Conclusion

Correction of uterine cavitary lesions makes the implantation rate and pregnancy rate to be comparable towomen with normal uterine cavity.