Background: Rheumatologic diseases are the most prevalent diseases orldwide. About one-third of physical disabilities in elderly are due to heumatologic etiological disorders as a primary cause. They are one of the main causes of disability and morbidity all over the world with great impact on the quality of life. Aim: The aim of this study was to examine the profiles of rheumatic diseases of the admitted patients to Assiut University hospital and to compare them with that of non-Arabic countries. Material and Methods: Descriptive study of 939 patients with heumatologic diseases during the period study (from January 2011 and April 2014). Diagnosis of the patients was done after fulfilling ACR/EULAR diagnostic criteria of each disease and required investigations were also done for verifying related diagnosis. Results: The total number of patients was 939, with (79.1%) female predominance. Age ranged from 7-79 years with a mean ± SD 38 ±15.32. Rheumatoid Arthritis (RA) was presented in 36.8%, Systemic Lupus Erythematosus (SLE) in 14.3%, Crystal Arthropathy in 11.7%, Seronegative Spondyloarthropathy (SpA) in 10.3%, Behçet disease (BD) in 8.3%, Juvenile Idiopathic Arthritis (JIA) in 6.4%, Systemic Sclerosis (SSc) in 5.8%, Overlap Syndrome in 2.9%, Antiphospholipid Syndrome (APS) in 0.3% and Adult onset Still`s Disease in 0.3%. Conclusion: Rheumatoid arthritis was the most common rheumatologic disease followed by Systemic Lupus Erythematosus in admitted patients of the Rheumatology, Rehabilitation, and Physical Medicine Department, Assiut University hospital.