Modified agglutination test (MAT) was applied to 150 chicken sera (90 were farm-bred and 60 house-bred chickens). The prevalence of Toxoplasma antibodies was 18.7%. In house-bred chickens positive cases were 18 out of 60 (30.0%), while in farm-bred chickens positive cases were 10 out of 90 (11.1%). Histopathological sections of the seropositive chickens showed tissue lesions which were most likely to be induced by T. gondii. Tissue cysts of T. gondii were demonstrated in the liver, brain, heart and skeletal muscles of 22 (78.6%) out of 28 positive chickens. These tissue cysts were found mostly in the brain of seropositive chickens. Epidemiological implications of these data for public health significance were discussed.

A series of identical twin esters 3a-e of metronidazole was synthesized and evaluated as potential prodrugs with improved physicochemical and pharmacokinetic properties. The synthesis of the twin esters 3a-e was achieved by interaction of metronidazole with the respective dicarboxylic acid anhydride or their dichloride. Their structures were verified by elemental and spectroscopic analyses. The lipophilicity of metronidazole and the prodrugs 3a-e, expressed as Rmvalues, were determined using reversed-phase TLC and revealed

A series of identical twin esters 3a-e of metronidazole was synthesized and evaluated as potential prodrugs with improved physicochemical and pharmacokinetic properties. The synthesis of the twin esters 3a-e was achieved by interaction of metronidazole with the respective dicarboxylic acid anhydride or their dichloride. Their structures were verified by elemental and spectroscopic analyses. The lipophilicity of metronidazole and the prodrugs 3a-e, expressed as Rmvalues, were determined using reversed-phase TLC and revealed

Aflatoxins are a type of mycotoxin produced by Aspergillus species of fungi, such as A. flavus and A. parasiticus. The umbrella term aflatoxin refers to four different types of mycotoxins produced, which are B1, B2, G1, and G2. Aflatoxin B1, the most toxic, is a potent carcinogen and has been directly correlated to adverse health effects, such as liver cancer, in many animal species. Aflatoxins are largely associated with commodities produced in the tropics and subtropics, such as cotton, peanuts, spices, pistachios and maize. As green Chemistry seeks to reduce the impact of chemistry on the environment by preventing the pollution at its source and using fewer natural resources, the present study shows the inhibition incidence of A. flavus by up to 90 percent by spraying the nuts, wheat or corn with yeast. Besides inhibiting the A. flavus fungus, yeast is found to be effective in protecting against any of at least half a dozen other species of microbes that can ruin a food's taste, texture, yield, safety or other attributes. The concentration of Aflatoxin B1 was traced using higher performance liquid chromatography before and after treatment.