Objective: to evaluate the possibility of using the Lund- Mackay radiological scoring system as a predictor of the extent of sinus surgery for nasal Polyposis by assessing the correlation between findings detected by this system and the extent of the performed surgery. Patients and methods: 116 patients, (222 nasal sides) were operated upon in this study. Preoperative CT scans were done within 48 hours prior to surgery, and interpreted by Lund- Mackay CT scoring system. Surgical procedures were done, and surgery score of the modified Lund-Mackay system was then applied and the relation between the two previous scores was evaluated after surgery. Results: Uncinectomy was done in 219 nasal sides. Middle meatballs antrostomy was done in 206 sides. Middle turbinate resection was done in 179 sides. Out of 214 sides for which anterior ethmoidectomy was done, 1 showed no sinus opacification in CT. While out of 8 sides for which anterior ethmoidectomy was not done, 1 showed partial opacification in CT. Posterior ethmoidectomy was done in 196 sides, 3 of them showed no sinus opacification in CT while 3 out of 26 sides for which posterior ethmoidectomy was not done showed complete sinus opacification in CT. On the other hand, 5 of 138 sides for which sphenoidotomy was done showed no sinus opacification in CT. Out of 100 sides for which frontal sinusotomy was done, 7 showed no opacification in CT. A strong correlation was found between the surgical and the radiological score (r = 0.8, p 0.001) Conclusions: Lund-Mackay radiological scoring of paranasal sinuses can strongly predict the extent of surgery for nasal polyposis.

Purpose: Our aim was to investigate the level and the maturation status of dendritic cells (DCs) in pediatric patients with sepsis and its relation to prognosis. Materials and methods: The study included 16 children with sepsis, 24 children with complicated sepsis, and 40 healthy control children. The patients were investigated within 24 hours of intensive care unit admission and after 28 days. Flow cytometric detection of DCs was done. Results: Within 24 hours, the levels of both plasmoid DCs and monocytoid DCs and the expression of CD86 and CD83 on DCs were significantly lower in patients than in controls, and the difference was marked in patients with complicated sepsis. The amount of CD86 and CD83 per cell was significantly lower in patients with complicated sepsis. The baseline numbers of monocytoid DCs and plasmoid DCs were higher in the survival patients than in nonsurvival patients. In addition, the expression of CD86 and CD83 on the entire DCs was significantly higher in the survival patients with sepsis. Conclusion: Sepsis is associated with reduced level of DCs and decreases their maturation. The estimation of DCs number and maturation state may be used as prognostic makers of sepsis.

Purpose: Our aim was to investigate the level and the maturation status of dendritic cells (DCs) in pediatric patients with sepsis and its relation to prognosis. Materials and methods: The study included 16 children with sepsis, 24 children with complicated sepsis, and 40 healthy control children. The patients were investigated within 24 hours of intensive care unit admission and after 28 days. Flow cytometric detection of DCs was done. Results: Within 24 hours, the levels of both plasmoid DCs and monocytoid DCs and the expression of CD86 and CD83 on DCs were significantly lower in patients than in controls, and the difference was marked in patients with complicated sepsis. The amount of CD86 and CD83 per cell was significantly lower in patients with complicated sepsis. The baseline numbers of monocytoid DCs and plasmoid DCs were higher in the survival patients than in nonsurvival patients. In addition, the expression of CD86 and CD83 on the entire DCs was significantly higher in the survival patients with sepsis. Conclusion: Sepsis is associated with reduced level of DCs and decreases their maturation. The estimation of DCs number and maturation state may be used as prognostic makers of sepsis.

Objective: the aim of this study was to assess wether total immunoglobulin E (IgE) levels and peripheral eosinophilia correlate with the extent of sinus mucosal disease on computed tomography (CT) of paranasal sinuses. patients and methods: CT scans were performed, total IgE and peripheral eosinophil levels were measured for all patients. The relationships between peripheral eosinophilia and IgE levels, and the presence of mucosal disease on sinus CT imaging were also determined. Results: The total IgE did not correlate with CT stage of the disease, whereas there was a significant moderate positive correlation between CT stage and peripheral eosinophil levels. conclusion:The data suggest that eosinophil levels contribute toward mucosal inflammation in paranasal sinuses and the presence of peripheral eosinophilia in patients with sinusitis indicates a high likelihood of extensive disease. However, IgE levels did not correlate with CT scan findings. Calculation of the percentage of peripheral eosinophils by measurement of differential leukocyte count is a simple, easy and rapid technique for assessment of the severity of chronic rhino sinusitis.

Objective: the aim of this study was to assess wether total immunoglobulin E (IgE) levels and peripheral eosinophilia correlate with the extent of sinus mucosal disease on computed tomography (CT) of paranasal sinuses. patients and methods: CT scans were performed, total IgE and peripheral eosinophil levels were measured for all patients. The relationships between peripheral eosinophilia and IgE levels, and the presence of mucosal disease on sinus CT imaging were also determined. Results: The total IgE did not correlate with CT stage of the disease, whereas there was a significant moderate positive correlation between CT stage and peripheral eosinophil levels. conclusion:The data suggest that eosinophil levels contribute toward mucosal inflammation in paranasal sinuses and the presence of peripheral eosinophilia in patients with sinusitis indicates a high likelihood of extensive disease. However, IgE levels did not correlate with CT scan findings. Calculation of the percentage of peripheral eosinophils by measurement of differential leukocyte count is a simple, easy and rapid technique for assessment of the severity of chronic rhino sinusitis.