Peripheral neuropathy in chronic obstructive pulmonary disease (COPD) has received scanty attention. The purpose of this study was to evaluate objectively the functional changes in the peripheral nervous system in COPD by different electrophysiological parameters and to determine the frequencies of these changes in patients with COPD. Aim of the study is assessment of peripheral nerve conduction by evaluation of the motor and sensory nerve conduction (SNC) in COPD patients.