Background

Vitiligo is an acquired, common, autoimmune, pigmentary defect of the skin. Vitamin D (VitD) plays a physiological role in photo-induced melanogenesis in the skin. It was found that VitD levels decline in autoimmune illnesses. Recently, there has been growing interest in the role of vitamin D3 in the pathogenesis of vitiligo and its change after treatment. The chemokine CXCL10 was found to be raised in the serum of patients with vitiligo. Few studies have evaluated its relation to the severity of the disease.

Aims

To establish a link between both serum VitD and serum CXCL10 and vitiligo, besides evaluating their possible relation to disease severity.