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Comparative Evaluation of Nanohydroxyapatite and Fluoride Containing Toothpastes on Dentinal Tubules Occlusion

Research Abstract

ABSTRACT
 

Aim: This investigation was conducted to compare the impact of three distinct toothpastes on
mineral deposition and dentinal tubules occlusion.
 

Material and Methods: Sixty dentin samples were prepared from sixty extracted molar. The
samples demineralized by submerging in 6% citric acid for two minutes. Then assigned into three
groups (n=20) according to the three different toothpastes utilized: Group A1: Fluoride containing
toothpaste. Group A2: Nano-hydroxyapatite containing toothpaste. Group A3: Nano-hydroxyapatite
with Fluoride containing toothpaste. For a total of two weeks, brushing was repeated twice a day
with a 12-hour interval between each session. Each sample were quantitatively assessed the ion
concentrations (atom%) on the dentin surface using Energy-dispersive Analytical X-ray (EDAX)
and qualitatively examined the dentinal tubules occlusion using Scanning Electron Microscope
(SEM).
 

Results: The lowest mean value of (Ca) % was found in (A1). The lowest mean (P) % value
observed in (A1). The lowest mean value of (F) % was recorded in (A2), while the greatest mean
value was identified in (A1 and A3).
 

Conclusion: Toothpastes containing nano-hydroxyapatite, both with and without fluoride,
show similar effects on mineral deposition and blockage of dentinal tubules.

Research Authors
Amany Abdel-Rahman Mahmoud 1 Nermin Alsayed Mahmoud 2
Research Date
Research Department
Research Journal
EGYPTIAN DENTAL JOURNAL
Research Member
Research Pages
2773:2782
Research Publisher
EGYPTIAN DENTAL JOURNAL
Research Rank
Local
Research Vol
71
Research Website
https://edj.journals.ekb.eg/article_440870.html
Research Year
2025