Breast cancer is the commonest malignant neoplasms among females in worldwide including Egypt. The study was carried out on 1070 out of a total of 1370 patients (78%) presenting with palpable breast lumps diagnosed with neoplastic breast lesions. Approximately one-third of the breast cancer patients diagnosed at age 40–50 years (median age range 49 (26-86 years); 71% came from rural areas; Positive family history was recorded in 7.5%. The patient herself detected the lump in the majority of cases (84%), only 40% sought medical advice with a specialist within the first four months. Accordingly, 62% of these patients presented in advanced stages (III and IV). The main histological type was the invasive ductal carcinoma, in which pathological changes of grade II and III were observed in 62.2% and 24.7% respectively. Conclusion: These findings of this study justify increasing efforts for establishing a comprehensive breast cancer control programs in Egypt for increasing awareness of the breast cancer and the controlling mechanisms as well as advocating for appropriate policies and programs for cancer control and early detection.